HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: LARG2 (Q8N3Y3)
Xylosyl- and glucuronyltransferase LARGE2 (EC 2.4.-.-) (Glycosyltransferase-like 1B) (LARGE xylosyl- and glucuronyltransferase 2) [Includes: Alpha-1,3-xylosyltransferase LARGE2 (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE2 (EC 2.4.1.-)]
Gene: LARGE2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1089 Hs			1 721
+	Hs
		314811 PGFRA_HUMAN (1-1089): 0: 817: 100.00		LARG1_HUMAN (60-711): 0: 989: 67.83
+	Hs
		557145 PGFRA_HUMAN (1-1089): 0: 817: 100.00		GXLT1_HUMAN (95-341): 3.18e-94: 301: 21.13
+	Hs
		49266 PGFRA_HUMAN (1-1089): 0: 817: 100.00		GXLT2_HUMAN (87-341): 3.94e-93: 298: 20.51
+	Hs
		987251 TYRO3_HUMAN (33-238): 3.34e-24: 111: 11.56		GXLT1_HUMAN (95-341): 3.18e-94: 301: 21.13
+	Hs
		607995 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		GXLT1_HUMAN (95-341): 3.18e-94: 301: 21.13