HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: PRPS1 (P60891)
Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase I) (PRS-I)
Gene: PRPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 318
+	Hs
		515798 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		PRPS2_HUMAN (1-318): 7.43e-180: 500: 95.28
+	Hs
		225839 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		KPRB_HUMAN (3-318): 4.84e-137: 394: 44.00
+	Hs
		557692 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		KPRA_HUMAN (3-318): 6.17e-132: 381: 42.98
+	Hs
		412112 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		PRPS1_HUMAN (1-318): 0: 507: 100.00
+	Hs
		442805 HCK_HUMAN (2-174): 4.07e-20: 93.7: 17.24		PRPS1_HUMAN (1-318): 0: 507: 100.00
+	Hs
		454819 FGR_HUMAN (7-150): 8.06e-20: 92.9: 20.00		PRPS1_HUMAN (1-318): 0: 507: 100.00
+	Hs
		411967 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		PRPS2_HUMAN (1-318): 7.43e-180: 500: 95.28
+	Hs
		442769 HCK_HUMAN (2-174): 4.07e-20: 93.7: 17.24		PRPS2_HUMAN (1-318): 7.43e-180: 500: 95.28
+	Hs
		454793 FGR_HUMAN (7-150): 8.06e-20: 92.9: 20.00		PRPS2_HUMAN (1-318): 7.43e-180: 500: 95.28
+	Hs
		225829 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		KPRB_HUMAN (3-318): 4.84e-137: 394: 44.00
+	Hs
		225830 HCK_HUMAN (2-174): 4.07e-20: 93.7: 17.24		KPRB_HUMAN (3-318): 4.84e-137: 394: 44.00
+	Hs
		412194 FYN_HUMAN (7-173): 7.47e-21: 96: 15.39		KPRA_HUMAN (3-318): 6.17e-132: 381: 42.98
+	Hs
		442829 HCK_HUMAN (2-174): 4.07e-20: 93.7: 17.24		KPRA_HUMAN (3-318): 6.17e-132: 381: 42.98
+	Hs
		454831 FGR_HUMAN (7-150): 8.06e-20: 92.9: 20.00		KPRA_HUMAN (3-318): 6.17e-132: 381: 42.98