Protein: COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (EC 2.1.1.201) (Ubiquinone biosynthesis methyltransferase COQ5)

Gene: COQ5
Organism: Homo sapiens
Interactions: 91
UniProt ID: Q5HYK3

Gene Ontology (top 5):
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix
GO:0006744 - ubiquinone biosynthetic process
GO:0008168 - methyltransferase activity
GO:0008425 - 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1126319

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

4

High-throughput

0.618

High

1126364

COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

2

1

Small-scale

0.584

High

824706

NPY2R
Neuropeptide Y receptor type 2

2

1

High-throughput

0.574

High

258460

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.561

High

1126363

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

1

1

High-throughput

0.561

High

262835

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

499802

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.536

High

380113

MAS
Proto-oncogene Mas

1

4

High-throughput

0.489

High

598952

FPR1
fMet-Leu-Phe receptor

1

3

High-throughput

0.489

High

674029

V2R
Vasopressin V2 receptor

1

1

High-throughput

0.489

High

723316

APJ
Apelin receptor

1

2

High-throughput

0.489

High

1030943

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.489

High

1126327

GTPB8
GTP-binding protein 8

1

1

High-throughput

0.489

High

1126345

CML1
Chemerin-like receptor 1

1

3

High-throughput

0.489

High

1126366

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.489

High

264923

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

440550

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.479

High

520713

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

2

High-throughput

0.479

High

1014387

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

1020446

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

2

High-throughput

0.479

High

1126323

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

1

High-throughput

0.479

High

1126329

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.479

High

1126331

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

1

High-throughput

0.479

High

1126333

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

1

High-throughput

0.479

High

1126334

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

1126335

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

1126336

COQ8B
Atypical kinase COQ8B, mitochondrial

1

1

High-throughput

0.479

High

1126337

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

1

High-throughput

0.479

High

1126339

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

2

High-throughput

0.479

High

1126341

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

3

High-throughput

0.479

High

1126343

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

1126344

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

1126346

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

1

High-throughput

0.479

High

1126359

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

4

High-throughput

0.479

High

1126361

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

1

High-throughput

0.479

High

1126365

DJC15
DnaJ homolog subfamily C member 15

1

1

High-throughput

0.479

High

63368

MET15
12S rRNA N4-methylcytidine

1

0

High-throughput

0.458

High

282082

CLPX
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial

1

0

High-throughput

0.458

High

327455

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

336875

OTC
Ornithine transcarbamylase, mitochondrial

1

0

High-throughput

0.458

High

777583

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

789824

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

799241

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

947398

RT35
Small ribosomal subunit protein mS35

1

0

High-throughput

0.458

High

981276

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

990095

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1045770

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1050970

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.458

High

1067977

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1126342

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

1126351

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.458

High

1126352

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

1126355

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1126356

L2HDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

1126357

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1126362

PDIP2
Polymerase delta-interacting protein 2

1

0

High-throughput

0.458

High

246356

SCN2B
Sodium channel subunit beta-2

1

1

High-throughput

0.437

High

270046

RF1M
Peptide chain release factor 1, mitochondrial

1

1

High-throughput

0.437

High

803128

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.437

High

1126347

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.437

High

1126350

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.437

High

1126353

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1126324

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

0

High-throughput

0.328

High

1126330

F174A
Membrane protein FAM174A

2

0

High-throughput

0.328

High

1126360

CCG4
Voltage-dependent calcium channel gamma-4 subunit

2

0

High-throughput

0.318

High

1126348

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

0.282

High

259852

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

0

High-throughput

0.279

Low

560278

DPEP1
Dipeptidase 1

1

0

High-throughput

0.279

Low

667974

SPB3
Serpin B3

1

0

High-throughput

0.279

Low

702232

CD70
CD70 antigen

1

0

High-throughput

0.279

Low

706901

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.279

Low

787739

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.279

Low

795534

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

0

High-throughput

0.279

Low

985339

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.279

Low

1126322

FBX50
F-box only protein 50

1

0

High-throughput

0.279

Low

1126326

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

1126328

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1126367

NPTN
Neuroplastin

1

0

High-throughput

0.279

Low

1126349

S13A1
Solute carrier family 13 member 1

1

0

Small-scale

0.251

Low

318638

EYA4
Eyes absent homolog 4

1

0

High-throughput

0.249

Low

1101085

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1126320

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.249

Low

1126321

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

Small-scale

0.249

Low

1126325

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.249

Low

1126332

SPRY4
SPRY domain-containing protein 4

1

0

High-throughput

0.249

Low

1126338

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.249

Low

1126340

PREY
Protein preY, mitochondrial

1

0

High-throughput

0.249

Low

1126354

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1126358

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.249

Low

353945

IGHM
Immunoglobulin heavy constant mu

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024