HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: U3KQK0 (U3KQK0)
Histone H2B
Gene: H2BC15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 166
+	Hs
		557647 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		H2B1D_HUMAN (1-126): 1.09e-57: 178: 99.21
+	Hs
		557738 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		H2B3B_HUMAN (1-126): 1.39e-55: 172: 96.03
+	Hs
		918279 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1C_HUMAN (1-126): 4.48e-58: 179: 99.21
+	Hs
		924623 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B2F_HUMAN (1-126): 2.54e-58: 179: 97.62
+	Hs
		924770 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1H_HUMAN (1-126): 3.64e-58: 179: 98.41
+	Hs
		241496 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1K_HUMAN (1-126): 5.4e-58: 178: 98.41
+	Hs
		883010 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2BFS_HUMAN (1-126): 8.09e-58: 178: 96.83
+	Hs
		886077 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1D_HUMAN (1-126): 1.09e-57: 178: 99.21
+	Hs
		924819 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1N_HUMAN (1-126): 1.1e-57: 178: 100.00
+	Hs
		924820 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1M_HUMAN (1-126): 7.92e-58: 178: 96.83
+	Hs
		924821 GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81		H2B1L_HUMAN (1-126): 1.5e-56: 175: 97.62