HitPredict

Interactor 1: RPB3 (P16370)
DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (B44.5) (DNA-directed RNA polymerase II 45 kDa polypeptide)
Gene: RPB3

Interactor 2: TF2B (P29055)
Transcription initiation factor IIB (General transcription factor TFIIB) (Transcription factor E)
Gene: SUA7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.719

Property	Details
Experiments	31304538, 34543624, 33888559, 34592154, 37863410, 19131970
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0046872 - metal ion binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 318 Sc			1 345
+	Sc
		557928 RPB3_YEAST (1-318): 3.91e-173: 484: 100.00		TF3B_YEAST (23-340): 1.67e-85: 271: 16.92
+	Hs
		583461 RPB3_HUMAN (6-270): 4.25e-119: 345: 45.19		TF2B_HUMAN (27-340): 2.69e-122: 356: 32.70
+	Sc
		429654 RPAC1_YEAST (3-258): 3.25e-89: 271: 23.31		TF2B_YEAST (1-345): 4.06e-145: 415: 100.00
+	At
		819498 Q39216_ARATH (4-263): 1.08e-88: 271: 24.52		TF2B1_ARATH (24-339): 6.82e-115: 337: 31.76
+	Hs
		169911 RPAC1_HUMAN (3-268): 1.5e-104: 311: 25.16		TF3B_HUMAN (20-316): 4.36e-89: 282: 19.33
+	Sc
		429655 RPAC1_YEAST (3-258): 3.25e-89: 271: 23.31		TF3B_YEAST (23-340): 1.67e-85: 271: 16.92