Protein: TF3C4
General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (TF3C-delta) (Transcription factor IIIC 90 kDa subunit) (TFIIIC 90 kDa subunit) (TFIIIC90) (Transcription factor IIIC subunit delta)

Gene: TF3C4, GTF3C4
Organism: Homo sapiens
Interactions: 165
UniProt ID: Q9UKN8

Gene Ontology (top 5):
GO:0000127 - transcription factor TFIIIC complex
GO:0000995 - RNA polymerase III general transcription initiation factor activity
GO:0003677 - DNA binding
GO:0004402 - histone acetyltransferase activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

348198

MYC
Myc proto-oncogene protein

5

1

High-throughput

0.706

High

1259926

TF3C2
General transcription factor 3C polypeptide 2

3

0

Small-scale

0.645

High

1016451

TF3C1
General transcription factor 3C polypeptide 1

3

0

Small-scale

0.642

High

861975

PLK1
Serine/threonine-protein kinase PLK1

2

1

High-throughput

0.628

High

1356541

TF3C5
General transcription factor 3C polypeptide 5

2

0

Small-scale

0.612

High

1269895

ESR2
Estrogen receptor beta

2

1

High-throughput

0.588

High

1356542

TF3C3
General transcription factor 3C polypeptide 3

2

0

Small-scale

0.585

High

487827

ANDR
Androgen receptor

2

1

High-throughput

0.584

High

935360

H31
Histone H3.1

2

3

High-throughput

0.584

High

66714

ZN785
Zinc finger protein 785

2

1

High-throughput

0.574

High

1312895

RPC3
DNA-directed RNA polymerase III subunit RPC3

2

0

Small-scale

0.569

High

229028

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

387704

P53
Cellular tumor antigen p53

2

0

High-throughput

0.559

High

918120

H4
Histone H4

2

0

High-throughput

0.559

High

1293123

ZN764
Zinc finger protein 764

2

2

High-throughput

0.549

High

1281133

TF3C6
General transcription factor 3C polypeptide 6

1

0

Small-scale

0.545

High

542765

ETS2
Protein C-ets-2

1

1

High-throughput

0.541

High

208953

FOXS1
Forkhead box protein S1

1

2

High-throughput

0.536

High

473726

ZN688
Zinc finger protein 688

1

3

High-throughput

0.536

High

789136

FRK
Tyrosine-protein kinase FRK

1

2

High-throughput

0.536

High

949910

CBX1
Chromobox protein homolog 1

1

2

High-throughput

0.536

High

993356

FOXM1
Forkhead box protein M1

1

4

High-throughput

0.536

High

1021377

FOXL1
Forkhead box protein L1

1

2

High-throughput

0.536

High

1335788

CBX8
Chromobox protein homolog 8

1

2

High-throughput

0.536

High

1349614

FOXJ2
Forkhead box protein J2

1

2

High-throughput

0.536

High

1234580

SH2D3
SH2 domain-containing protein 3C

2

1

High-throughput

0.521

High

133726

NOP56
Nucleolar protein 56

1

0

High-throughput

0.513

High

238286

RAD1
Cell cycle checkpoint protein RAD1

1

0

High-throughput

0.513

High

375070

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.513

High

418774

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

587055

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

908206

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

943015

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.513

High

987014

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.513

High

1058061

RRP5
Protein RRP5 homolog

1

0

High-throughput

0.513

High

1060645

ZN638
Zinc finger protein 638

1

0

High-throughput

0.513

High

1061397

PSME4
Proteasome activator complex subunit 4

1

0

High-throughput

0.513

High

1199112

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

0

High-throughput

0.513

High

1355153

LIMD1
LIM domain-containing protein 1

1

0

High-throughput

0.513

High

1174684

H32
Histone H3.2

1

3

Small-scale

0.501

High

175728

TRI18
E3 ubiquitin-protein ligase Midline-1

1

1

High-throughput

0.489

High

796672

KSYK
Tyrosine-protein kinase SYK

1

3

High-throughput

0.489

High

862126

DAPK1
Death-associated protein kinase 1

1

1

High-throughput

0.489

High

1300882

PASK
PAS domain-containing serine/threonine-protein kinase

1

1

High-throughput

0.489

High

1306880

FOXB1
Forkhead box protein B1

1

5

High-throughput

0.489

High

1313624

ZN747
Zinc finger protein 747

1

3

High-throughput

0.489

High

1318661

FOXQ1
Forkhead box protein Q1

1

4

High-throughput

0.489

High

749946

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.481

High

160844

AURKA
Aurora kinase A

1

0

Small-scale

0.480

High

589935

TBP
TATA-box-binding protein

1

0

Small-scale

0.480

High

902803

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

1328666

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

0

Small-scale

0.480

High

261036

H2AY
Core histone macro-H2A.1

1

1

High-throughput

0.479

High

337587

ABL1
Tyrosine-protein kinase ABL1

1

2

High-throughput

0.479

High

380003

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

442582

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

669064

PML
Protein PML

1

2

High-throughput

0.479

High

707786

H2B1B
Histone H2B type 1-B

1

1

High-throughput

0.479

High

708542

MCM4
DNA replication licensing factor MCM4

1

2

High-throughput

0.479

High

828419

CENPA
Histone H3-like centromeric protein A

1

3

High-throughput

0.479

High

832771

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

877385

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

1

High-throughput

0.479

High

918767

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

944987

RED1
Double-stranded RNA-specific editase 1

1

1

High-throughput

0.479

High

952691

H33
Histone H3.3

1

3

High-throughput

0.479

High

1027322

CBX3
Chromobox protein homolog 3

1

2

High-throughput

0.479

High

1030004

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

1055655

MCM6
DNA replication licensing factor MCM6

1

2

High-throughput

0.479

High

1057421

SMC1A
Structural maintenance of chromosomes protein 1A

1

1

High-throughput

0.479

High

1086029

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1153969

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.479

High

1198291

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

1

Small-scale

0.479

High

1304171

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

1305977

BARD1
BRCA1-associated RING domain protein 1

1

2

High-throughput

0.479

High

1313311

MET22
Methyltransferase-like protein 22

1

1

High-throughput

0.479

High

1356538

SMC3
Structural maintenance of chromosomes protein 3

1

1

High-throughput

0.479

High

1356540

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

High-throughput

0.479

High

123079

MEN1
Menin

1

0

High-throughput

0.458

High

179880

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

182947

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

245077

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

268329

EED
Polycomb protein EED

1

0

High-throughput

0.458

High

295382

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

391962

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.458

High

524071

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

570168

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

595467

LMNB1
Lamin-B1

1

0

High-throughput

0.458

High

622543

CCND1
G1/S-specific cyclin-D1

1

0

High-throughput

0.458

High

719222

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

750529

COIL
Coilin

1

0

High-throughput

0.458

High

809008

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.458

High

826372

CDK8
Cyclin-dependent kinase 8

1

0

High-throughput

0.458

High

941569

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

961315

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

968005

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1019172

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1035293

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

0

High-throughput

0.458

High

1042813

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1063676

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1080465

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1183785

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.458

High

1200743

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1236564

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1256469

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1291128

CDCA5
Sororin

1

0

High-throughput

0.458

High

1300988

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

1314423

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1331201

SENP3
Sentrin-specific protease 3

1

0

Small-scale

0.458

High

1331260

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

0

High-throughput

0.458

High

1332753

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1334044

WDR76
WD repeat-containing protein 76

1

0

High-throughput

0.458

High

1334440

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1343772

ANLN
Anillin

1

0

High-throughput

0.458

High

1348381

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1348903

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1350117

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1354812

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1356536

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

1356543

NS1BP
Influenza virus NS1A-binding protein

1

0

High-throughput

0.458

High

1344821

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

149407

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.437

High

229750

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

1

High-throughput

0.437

High

789097

ABL2
Tyrosine-protein kinase ABL2

1

2

High-throughput

0.437

High

1139792

MT21C
Protein-lysine methyltransferase METTL21C

1

1

High-throughput

0.437

High

1172211

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1331595

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

275477

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.426

High

1039929

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

1130711

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1318891

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

1356534

AGO1
Protein argonaute-1

1

0

High-throughput

0.426

High

166469

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.279

Low

949073

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

1040961

MTMR3
Myotubularin-related protein 3

1

0

High-throughput

0.279

Low

1199453

LYRIC
Protein LYRIC

1

0

High-throughput

0.279

Low

1329988

PABP3
Polyadenylate-binding protein 3

1

0

High-throughput

0.279

Low

1331900

ZN644
Zinc finger protein 644

1

0

High-throughput

0.279

Low

1344753

SNRK
SNF-related serine/threonine-protein kinase

1

0

High-throughput

0.279

Low

1344967

LATS2
Serine/threonine-protein kinase LATS2

1

0

High-throughput

0.279

Low

1346800

FAIM1
Fas apoptotic inhibitory molecule 1

1

0

High-throughput

0.279

Low

1354485

CLIP2
CAP-Gly domain-containing linker protein 2

1

0

High-throughput

0.279

Low

1356537

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

0

High-throughput

0.279

Low

1356539

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

59432

SBNO1
Protein strawberry notch homolog 1

1

0

High-throughput

0.249

Low

101272

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

298876

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

330009

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

385696

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

932443

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.249

Low

959754

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

1021473

ANK3
Ankyrin-3

1

0

High-throughput

0.249

Low

1061967

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

1

0

High-throughput

0.249

Low

1066852

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

1101369

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1174325

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.249

Low

1189020

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1231369

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

1243991

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1294123

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1329616

ADNP
Activity-dependent neuroprotector homeobox protein

1

0

High-throughput

0.249

Low

1353927

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

0

High-throughput

0.249

Low

1354403

ZMYM2
Zinc finger MYM-type protein 2

1

0

High-throughput

0.249

Low

1356535

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

331108

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.232

Low

1334595

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024