HitPredict

Interactor 1: GROU (P16371)
Protein groucho (Enhancer of split m9/10 protein) (E(spl)m9/10)
Gene: gro

Interactor 2: Q9GRA9 (Q9GRA9)
Master of thick veins
Gene: sbb

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17571073
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 730 Dm			1 2310
+	Dm
		558390 GROU_DROME (1-730): 4.17e-172: 513: 100.00		Q9N693_DROME (19-2310): 2.39e-160: 553: 99.65
+	Hs
		980906 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		ZN608_HUMAN (749-1215): 8.32e-37: 155: 29.45
+	Hs
		164216 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		ZN609_HUMAN (642-2022): 2.75e-34: 147: 16.25
+	Hs
		131716 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		BCL9_HUMAN (1311-2309): 3.98e-13: 77.5: 9.46
+	Hs
		146201 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		ARI1A_HUMAN (1163-2049): 7.44e-11: 70.2: 9.36
+	Hs
		980830 TLE3_HUMAN (1-730): 2.82e-146: 447: 57.27		CBP_HUMAN (1051-2093): 7.07e-09: 63.8: 10.31
+	Hs
		993473 TLE5_HUMAN (1-197): 8.88e-84: 265: 49.51		ANR11_HUMAN (1371-2121): 4.51e-11: 71.1: 11.31
+	Hs
		903598 WDR5_HUMAN (615-729): 8.81e-35: 137: 18.80		ZN608_HUMAN (749-1215): 8.32e-37: 155: 29.45
+	Hs
		1288379 SNR40_HUMAN (566-728): 3.08e-32: 130: 20.96		ZN608_HUMAN (749-1215): 8.32e-37: 155: 29.45
+	Hs
		164257 SNR40_HUMAN (566-728): 3.08e-32: 130: 20.96		ZN609_HUMAN (642-2022): 2.75e-34: 147: 16.25
+	Dm
		1358850 WDS_DROME (565-728): 5.12e-51: 183: 19.76		NUP98_DROME (36-795): 3.2e-17: 91.1: 11.26
+	Hs
		903229 WDR5_HUMAN (615-729): 8.81e-35: 137: 18.80		NCOA6_HUMAN (718-2306): 9.75e-30: 132: 10.27
+	Mm
		903669 WDR5_MOUSE (615-729): 8.81e-35: 137: 18.80		KMT2C_MOUSE (1583-2155): 5.28e-15: 84.2: 12.83
+	Dm
		113977 GBLP_DROME (564-728): 2.96e-36: 141: 15.00		M9PB30_DROME (1860-2310): 6.17e-12: 74: 11.04
+	Hs
		857957 WDR5_HUMAN (615-729): 8.81e-35: 137: 18.80		NUP98_HUMAN (3-523): 4.93e-13: 77.5: 9.81
+	Hs
		131738 SNR40_HUMAN (566-728): 3.08e-32: 130: 20.96		BCL9_HUMAN (1311-2309): 3.98e-13: 77.5: 9.46
+	Hs
		903374 WDR5_HUMAN (615-729): 8.81e-35: 137: 18.80		KMT2C_HUMAN (1726-2262): 1.44e-10: 69.6: 12.90
+	Hs
		903405 WDR5_HUMAN (615-729): 8.81e-35: 137: 18.80		CBP_HUMAN (1051-2093): 7.07e-09: 63.8: 10.31
+	Hs
		146265 SNR40_HUMAN (566-728): 3.08e-32: 130: 20.96		ARI1A_HUMAN (1163-2049): 7.44e-11: 70.2: 9.36