HitPredict

Interactor 1: 7UP1 (P16375)
Steroid receptor seven-up, isoforms B/C (Nuclear receptor subfamily 2 group F member 3, isoforms B/C)
Gene: svp

Interactor 2: ABDA (P29555)
Homeobox protein abdominal-A
Gene: abd-A

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	25869471, 30247122
Identification Methods	affinity chromatography technology, protein complementation assay
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0007507 - heart development GO:0014019 - neuroblast development
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 543 Dm			1 590
+	Dm
		558426 7UP1_DROME (1-543): 4.28e-179: 517: 100.00		UBX_DROME (286-464): 7.93e-37: 143: 40.58
+	Dm
		367172 7UP1_DROME (1-543): 4.28e-179: 517: 100.00		ANTP_DROME (300-478): 3.78e-36: 141: 38.17
+	Dm
		558422 7UP1_DROME (1-543): 4.28e-179: 517: 100.00		ZFH2_DROME (396-485): 2.54e-12: 72.4: 21.11
+	Dm
		668233 HNF4_DROME (89-542): 1.82e-107: 338: 29.19		ABDA_DROME (1-590): 6.66e-69: 235: 100.00
+	Hs
		446867 RXRG_HUMAN (66-533): 1.61e-130: 390: 32.84		HXD4_HUMAN (272-491): 1.44e-28: 116: 29.55
+	Dm
		836359 HNF4_DROME (89-542): 1.82e-107: 338: 29.19		UBX_DROME (286-464): 7.93e-37: 143: 40.58
+	Hs
		487977 RARA_HUMAN (110-537): 3.79e-111: 340: 25.47		ALX1_HUMAN (307-544): 5.03e-32: 128: 16.32
+	Hs
		377352 GCR_HUMAN (75-538): 2.31e-98: 316: 24.60		ALX1_HUMAN (307-544): 5.03e-32: 128: 16.32
+	Hs
		370576 ESR1_HUMAN (96-529): 1.08e-107: 336: 22.92		HXC10_HUMAN (399-458): 5.95e-15: 78.2: 68.33
+	Hs
		824472 NR2C2_HUMAN (200-276): 2.24e-32: 133: 70.13		VSX1_HUMAN (226-497): 8.04e-35: 137: 18.32
+	Hs
		824253 NR2C2_HUMAN (200-276): 2.24e-32: 133: 70.13		LHX4_HUMAN (374-587): 8.68e-29: 120: 16.89