HitPredict

Interactor 1: IL4RA (P16382)
Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha) (IL-4R subunit alpha) (IL-4R-alpha) (IL-4RA) (CD antigen CD124) [Cleaved into: Soluble interleukin-4 receptor subunit alpha (Soluble IL-4 receptor subunit alpha) (Soluble IL-4R-alpha) (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)]
Gene: Il4r

Interactor 2: STAT3 (P42227)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19282476
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0019221 - cytokine-mediated signaling pathway GO:0042127 - regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 810 Mm			1 770
+	Mm
		558505 IL4RA_MOUSE (1-810): 0: 1118: 100.00		STAT6_MOUSE (1-761): 0: 668: 25.69
+	Hs
		622729 IL4RA_HUMAN (1-800): 0: 1050: 52.33		STAT6_HUMAN (1-753): 0: 627: 24.10
+	Hs
		540449 IL2RB_HUMAN (22-288): 2.11e-58: 210: 15.49		STAT3_HUMAN (1-770): 0: 1047: 99.87
+	Hs
		770182 IL6RB_HUMAN (22-229): 6.57e-38: 154: 18.81		STAT3_HUMAN (1-770): 0: 1047: 99.87
+	Hs
		562528 IL7RA_HUMAN (101-273): 1.09e-34: 140: 19.78		STAT3_HUMAN (1-770): 0: 1047: 99.87
+	Hs
		540451 IL2RB_HUMAN (22-288): 2.11e-58: 210: 15.49		STAT1_HUMAN (1-749): 0: 929: 51.52
+	Hs
		500951 GHR_HUMAN (15-286): 1.01e-14: 80.2: 14.53		STAT3_HUMAN (1-770): 0: 1047: 99.87
+	Hs
		786348 I13R2_HUMAN (3-245): 6.07e-52: 187: 14.94		STAT1_HUMAN (1-749): 0: 929: 51.52
+	Hs
		540463 IL2RB_HUMAN (22-288): 2.11e-58: 210: 15.49		STAT4_HUMAN (1-729): 0: 893: 48.44
+	Hs
		770183 IL6RB_HUMAN (22-229): 6.57e-38: 154: 18.81		STAT1_HUMAN (1-749): 0: 929: 51.52
+	Hs
		562532 IL7RA_HUMAN (101-273): 1.09e-34: 140: 19.78		STAT1_HUMAN (1-749): 0: 929: 51.52
+	Hs
		1059007 I12R2_HUMAN (30-231): 2.18e-19: 95.6: 14.01		STAT4_HUMAN (1-729): 0: 893: 48.44
+	Mm
		557513 IL2RB_MOUSE (20-302): 1.33e-60: 216: 18.36		STA5B_MOUSE (1-734): 0: 760: 30.59
+	Mm
		557512 IL2RB_MOUSE (20-302): 1.33e-60: 216: 18.36		STA5A_MOUSE (1-734): 0: 758: 30.46
+	Hs
		540455 IL2RB_HUMAN (22-288): 2.11e-58: 210: 15.49		STA5B_HUMAN (1-734): 0: 752: 30.55
+	Hs
		540452 IL2RB_HUMAN (22-288): 2.11e-58: 210: 15.49		STA5A_HUMAN (1-734): 0: 745: 30.42
+	Hs
		562533 IL7RA_HUMAN (101-273): 1.09e-34: 140: 19.78		STA5A_HUMAN (1-734): 0: 745: 30.42
+	Mm
		786650 PRLR_MOUSE (33-284): 7.08e-16: 83.7: 13.08		STA5A_MOUSE (1-734): 0: 758: 30.46
+	Hs
		560469 PRLR_HUMAN (32-341): 2.84e-17: 88.3: 13.71		STA5B_HUMAN (1-734): 0: 752: 30.55
+	Hs
		500954 GHR_HUMAN (15-286): 1.01e-14: 80.2: 14.53		STA5B_HUMAN (1-734): 0: 752: 30.55