HitPredict

Interactor 1: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29509190, 21182203
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 530
+	Hs
		559459 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368931 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		559553 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Hs
		488904 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30