HitPredict

Interactor 1: EPCAM (P16422)
Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326)
Gene: EPCAM

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 314 Hs			1 839
+	Hs
		507833 EPCAM_HUMAN (1-314): 2.71e-154: 436: 100.00		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		560126 EPCAM_HUMAN (1-314): 2.71e-154: 436: 100.00		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		434131 EPCAM_HUMAN (1-314): 2.71e-154: 436: 100.00		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		560133 EPCAM_HUMAN (1-314): 2.71e-154: 436: 100.00		DDR2_HUMAN (527-824): 2.05e-70: 250: 43.30