HitPredict

Interactor 1: TSHR (P16473)
Thyrotropin receptor (Thyroid-stimulating hormone receptor) (TSH-R)
Gene: TSHR

Interactor 2: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	28298427
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016323 - basolateral plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 764 Hs			1 236
+	Hs
		722930 ADA1A_HUMAN (386-704): 3.75e-64: 223: 15.62		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		428997 ADRB2_HUMAN (393-721): 1.48e-63: 219: 17.52		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		887838 5HT4R_HUMAN (417-762): 2.4e-60: 210: 18.54		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		428955 ADRB2_HUMAN (393-721): 1.48e-63: 219: 17.52		TSN7_HUMAN (1-234): 7.1e-56: 180: 22.31
+	Hs
		428918 ADRB2_HUMAN (393-721): 1.48e-63: 219: 17.52		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		783912 5HT4R_HUMAN (417-762): 2.4e-60: 210: 18.54		TSN7_HUMAN (1-234): 7.1e-56: 180: 22.31
+	Hs
		208446 OX2R_HUMAN (409-735): 4.24e-60: 211: 16.36		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		326031 NK3R_HUMAN (396-753): 6.42e-60: 211: 16.67		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		237791 OPRX_HUMAN (420-708): 1.44e-60: 210: 19.54		TSN3_HUMAN (4-236): 1.19e-43: 149: 18.88
+	Hs
		326029 AA2BR_HUMAN (415-710): 2.75e-54: 192: 17.28		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		326201 LGR4_HUMAN (223-392): 7.61e-18: 90.5: 13.79		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48