Protein: SNX2
Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9)

Gene: SNX2
Organism: Homo sapiens
Interactions: 162
UniProt ID: O60749

Gene Ontology (top 5):
GO:0005154 - epidermal growth factor receptor binding
GO:0005158 - insulin receptor binding
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0005768 - endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

240456

SNX6
Sorting nexin-6

7

19

Small-scale

0.963

High

240386

SNX1
Sorting nexin-1

5

19

Small-scale

0.926

High

240410

SNX32
Sorting nexin-32

4

19

High-throughput

0.902

High

240458

DYN3
Dynamin-3

3

13

High-throughput

0.861

High

240464

SNX5
Sorting nexin-5

2

19

High-throughput

0.793

High

240322

SNX4
Sorting nexin-4

2

19

Small-scale

0.789

High

240323

VAPB
Vesicle-associated membrane protein-associated protein B/C

3

3

High-throughput

0.667

High

240374

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

3

1

High-throughput

0.667

High

240416

CAST3
Putative protein CASTOR3P

3

1

High-throughput

0.667

High

240366

DYN2
Dynamin-2

1

13

High-throughput

0.665

High

240433

FNBP1
Formin-binding protein 1

2

6

Small-scale

0.640

High

240399

HENMT
Small RNA 2'-O-methyltransferase

2

1

High-throughput

0.628

High

240422

DYT2B
Dynein light chain Tctex-type protein 2B

2

1

High-throughput

0.628

High

148192

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.618

High

240441

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.618

High

59505

F221A
Protein FAM221A

3

2

High-throughput

0.609

High

240398

TRML2
Trem-like transcript 2 protein

3

1

High-throughput

0.609

High

240415

CK042
Uncharacterized protein C11orf42

3

1

High-throughput

0.609

High

238125

PLIN3
Perilipin-3

2

2

High-throughput

0.606

High

240390

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

2

5

High-throughput

0.606

High

240421

TM239
Transmembrane protein 239

2

1

High-throughput

0.606

High

240317

SNX2
Sorting nexin-2

1

19

Small-scale

0.590

High

204807

TGON2
Trans-Golgi network integral membrane protein 2

2

8

High-throughput

0.588

High

226010

PRKN
E3 ubiquitin-protein ligase parkin

2

11

High-throughput

0.584

High

240325

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.584

High

240348

RAB4A
Ras-related protein Rab-4A

2

11

High-throughput

0.584

High

240376

RB11A
Ras-related protein Rab-11A

2

9

High-throughput

0.584

High

240385

MTM1
Myotubularin

2

4

High-throughput

0.584

High

240453

ZRAN1
Ubiquitin thioesterase ZRANB1

2

6

High-throughput

0.584

High

240405

CENPQ
Centromere protein Q

2

0

High-throughput

0.580

High

240434

PNKP
Bifunctional polynucleotide phosphatase/kinase

2

0

High-throughput

0.580

High

240438

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.580

High

240414

CA087
Uncharacterized protein C1orf87

2

2

High-throughput

0.574

High

240329

CP1A1
Cytochrome P450 1A1

2

1

High-throughput

0.558

High

240320

YIF1A
Protein YIF1A

2

1

High-throughput

0.553

High

240340

TAU
Microtubule-associated protein tau

2

4

High-throughput

0.552

High

240445

PAK6
Serine/threonine-protein kinase PAK 6

1

7

High-throughput

0.541

High

240467

DUS10
Dual specificity protein phosphatase 10

1

1

High-throughput

0.541

High

240318

DNJB6
DnaJ homolog subfamily B member 6

1

4

High-throughput

0.536

High

240336

GNAO

1

5

High-throughput

0.536

High

240350

BMP6
Bone morphogenetic protein 6

1

3

High-throughput

0.536

High

240352

1433T
14-3-3 protein theta

1

7

High-throughput

0.536

High

240354

TPP2
Tripeptidyl-peptidase 2

1

1

High-throughput

0.536

High

240371

S12A3
Solute carrier family 12 member 3

1

3

High-throughput

0.536

High

240373

1433G
14-3-3 protein gamma

1

7

High-throughput

0.536

High

240380

1433F
14-3-3 protein eta

1

7

High-throughput

0.536

High

240400

ECM29
Proteasome adapter and scaffold protein ECM29

1

2

High-throughput

0.536

High

240412

CBCO1
Ciliary-associated calcium-binding coiled-coil protein 1

1

2

High-throughput

0.536

High

240420

PRUN2
Protein prune homolog 2

1

2

High-throughput

0.536

High

240435

CDC5L
Cell division cycle 5-like protein

1

3

High-throughput

0.536

High

240443

SDF2L
Stromal cell-derived factor 2-like protein 1

1

2

High-throughput

0.536

High

240446

KLHL1
Kelch-like protein 1

1

4

High-throughput

0.536

High

240452

DJB11
DnaJ homolog subfamily B member 11

1

2

High-throughput

0.536

High

240454

NRBP
Nuclear receptor-binding protein

1

3

High-throughput

0.536

High

240455

SPAT2
Spermatogenesis-associated protein 2

1

1

High-throughput

0.536

High

240461

WASC3
WASH complex subunit 3

1

1

High-throughput

0.536

High

240462

HYOU1
Hypoxia up-regulated protein 1

1

5

High-throughput

0.536

High

240465

SAR1B
Small COPII coat GTPase SAR1B

1

9

High-throughput

0.536

High

240330

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.515

High

240360

HD
Huntingtin

1

2

High-throughput

0.515

High

240324

CYB5
Cytochrome b5

1

0

High-throughput

0.513

High

240404

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.513

High

240463

TRI17
E3 ubiquitin-protein ligase TRIM17

1

0

High-throughput

0.513

High

48853

POTB3
POTE ankyrin domain family member B3

2

5

High-throughput

0.504

High

240395

SMN
Survival motor neuron protein

1

0

High-throughput

0.493

High

240419

GDAP1
Ganglioside-induced differentiation-associated protein 1

1

0

High-throughput

0.493

High

147198

CUX2
Homeobox protein cut-like 2

1

3

High-throughput

0.489

High

240338

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

240383

FOXL1
Forkhead box protein L1

1

3

High-throughput

0.489

High

240397

DB136
Defensin beta 136

1

3

High-throughput

0.489

High

240423

IBPL1
Insulin-like growth factor-binding protein-like 1

1

7

High-throughput

0.489

High

240460

NTNG1
Netrin-G1

1

6

High-throughput

0.489

High

240466

RM42
Large ribosomal subunit protein mL42

1

1

High-throughput

0.489

High

240377

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.481

High

178324

STX7
Syntaxin-7

1

7

High-throughput

0.479

High

212686

STX6
Syntaxin-6

1

4

High-throughput

0.479

High

240326

TFR1
Transferrin receptor protein 1

1

3

High-throughput

0.479

High

240327

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

240328

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

240331

K1C18
Keratin, type I cytoskeletal 18

1

1

High-throughput

0.479

High

240332

INSR
Insulin receptor

1

20

Small-scale

0.479

High

240333

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.479

High

240337

PGFRB
Platelet-derived growth factor receptor beta

1

15

Small-scale

0.479

High

240339

PARP1
Poly [ADP-ribose] polymerase 1

1

6

High-throughput

0.479

High

240342

FGFR1
Fibroblast growth factor receptor 1

1

14

High-throughput

0.479

High

240343

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

240344

LAMP2
Lysosome-associated membrane glycoprotein 2

1

15

High-throughput

0.479

High

240346

PGFRA
Platelet-derived growth factor receptor alpha

1

15

Small-scale

0.479

High

240347

GNAT2
Guanine nucleotide-binding protein G(t) subunit alpha-2

1

5

High-throughput

0.479

High

240349

RAB5A
Ras-related protein Rab-5A

1

14

High-throughput

0.479

High

240351

FGFR4
Fibroblast growth factor receptor 4

1

14

High-throughput

0.479

High

240355

MARCS
Myristoylated alanine-rich C-kinase substrate

1

3

High-throughput

0.479

High

240356

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

240358

VGFR3
Vascular endothelial growth factor receptor 3

1

14

High-throughput

0.479

High

240359

ACV1B
Activin receptor type-1B

1

8

Small-scale

0.479

High

240361

YAP1
Transcriptional coactivator YAP1

1

8

High-throughput

0.479

High

240364

GSK3A
Glycogen synthase kinase-3 alpha

1

2

High-throughput

0.479

High

240365

GSK3B
Glycogen synthase kinase-3 beta

1

2

High-throughput

0.479

High

240367

RAB5C
Ras-related protein Rab-5C

1

14

High-throughput

0.479

High

240368

RAB7A
Ras-related protein Rab-7a

1

18

High-throughput

0.479

High

240369

RAB9A
Ras-related protein Rab-9A

1

17

High-throughput

0.479

High

240375

ARF6
ADP-ribosylation factor 6

1

6

High-throughput

0.479

High

240378

RHOG
Rho-related GTP-binding protein RhoG

1

5

High-throughput

0.479

High

240379

IFM3
Interferon-induced transmembrane protein 3

1

5

High-throughput

0.479

High

240384

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

240387

AVR2B
Activin receptor type-2B

1

8

Small-scale

0.479

High

240392

RAB35
Ras-related protein Rab-35

1

7

High-throughput

0.479

High

240393

RHOH
Rho-related GTP-binding protein RhoH

1

7

High-throughput

0.479

High

240394

T22D1
TSC22 domain family protein 1

1

2

High-throughput

0.479

High

240401

LTOR1
Ragulator complex protein LAMTOR1

1

8

High-throughput

0.479

High

240403

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

240406

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.479

High

240417

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.479

High

240424

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

1

High-throughput

0.479

High

240425

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

240427

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.479

High

240429

AURKB
Aurora kinase B

1

6

High-throughput

0.479

High

240432

FMNL2
Formin-like protein 2

1

3

High-throughput

0.479

High

240436

WWTR1
WW domain-containing transcription regulator protein 1

1

8

High-throughput

0.479

High

240439

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

1

Small-scale

0.479

High

240440

DNJC5
DnaJ homolog subfamily C member 5

1

11

High-throughput

0.479

High

240442

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

240444

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

Small-scale

0.479

High

240448

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

240450

ANFY1
Rabankyrin-5

1

6

High-throughput

0.479

High

240451

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

240459

LAMP3
Lysosome-associated membrane glycoprotein 3

1

15

High-throughput

0.479

High

240389

NFYC
Nuclear transcription factor Y subunit gamma

1

0

High-throughput

0.460

High

176076

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.458

High

240319

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

240335

K1C19
Keratin, type I cytoskeletal 19

1

0

High-throughput

0.458

High

240388

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.458

High

240391

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

240396

FSCN1
Fascin

1

0

High-throughput

0.458

High

240408

HOOK3
Protein Hook homolog 3

1

0

High-throughput

0.458

High

240418

FXL13
F-box and leucine-rich repeat protein 13

1

0

Small-scale

0.458

High

240437

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

240382

WASC5
WASH complex subunit 5

1

1

High-throughput

0.445

High

240321

ZN202
Zinc finger protein 202

1

1

High-throughput

0.439

High

240345

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

240353

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

240357

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

240362

LEPR
Leptin receptor

1

4

Small-scale

0.437

High

240363

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.437

High

240370

EPHA5
Ephrin type-A receptor 5

1

18

High-throughput

0.437

High

240372

RAB25
Ras-related protein Rab-25

1

9

High-throughput

0.437

High

240381

FHI1A
FHF complex subunit HOOK-interacting protein 1A

1

5

High-throughput

0.437

High

240407

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.437

High

240409

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

240411

F90A1
Protein FAM90A1

1

3

High-throughput

0.437

High

240413

ZDH23
Palmitoyltransferase ZDHHC23

1

5

Small-scale

0.437

High

240426

ESR2
Estrogen receptor beta

1

3

High-throughput

0.437

High

240447

ZDH18
Palmitoyltransferase ZDHHC18

1

2

Small-scale

0.437

High

240457

TRI33
E3 ubiquitin-protein ligase TRIM33

1

1

High-throughput

0.437

High

240428

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

240449

VAPA
Vesicle-associated membrane protein-associated protein A

1

3

Small-scale

0.408

High

240341

LAMC1
Laminin subunit gamma-1

1

0

High-throughput

0.251

Low

240402

CA122
Uncharacterized protein C1orf122

1

0

High-throughput

0.251

Low

240334

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.249

Low

240430

BORC6
BLOC-1-related complex subunit 6

1

0

High-throughput

0.249

Low

240431

SFXN2
Sideroflexin-2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024