Interactor 1: BIP (P16474)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein homolog) (GRP-78) (Immunoglobulin heavy chain-binding protein homolog) (BiP)
Gene: KAR2

Interactor 2: HRD3 (Q05787)
ERAD-associated E3 ubiquitin-protein ligase component HRD3 (HMG-CoA reductase degradation protein 3)
Gene: HRD3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 25428985
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002235 - detection of unfolded protein
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0034099 - luminal surveillance complex
GO:0036503 - ERAD pathway
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 682
Sc

1 833
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs

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Last updated: 15 Jul 2024