Interactor 1: HEM1 (P13196)
5-aminolevulinate synthase, non-specific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1)
Gene: ALAS1

Interactor 2: HEMH (P22830)
Ferrochelatase, mitochondrial (EC 4.98.1.1) (Heme synthase) (Protoheme ferro-lyase)
Gene: FECH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 36836934
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix
GO:0006783 - heme biosynthetic process
GO:0006784 - heme A biosynthetic process
and 5 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 640
Hs

1 423
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025