Interactor 1: NEC2 (P16519)
Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (KEX2-like endoprotease 2) (Prohormone convertase 2) (Proprotein convertase 2) (PC2)
Gene: PCSK2
Interactor 2: NEC2 (P16519)
Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (KEX2-like endoprotease 2) (Prohormone convertase 2) (Proprotein convertase 2) (PC2)
Gene: PCSK2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 3597357 |
| Identification Methods | molecular sieving |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | P_proprotein~Peptidase_S8, Peptidase_S8~Peptidase_S8 |
| Common GO terms | GO:0004252 - serine-type endopeptidase activity GO:0005615 - extracellular space GO:0005654 - nucleoplasm GO:0006508 - proteolysis GO:0007399 - nervous system development and 12 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Zm | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Bs | |
|
|||||||||||
| + | Tk | |
|
|||||||||||
| + | Pf | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
