HitPredict

Interactor 1: NUMB (P16554)
Protein numb
Gene: NUMB

Interactor 2: NUMB (P16554)
Protein numb
Gene: NUMB

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

The method score is based on:

Property	Details
Experiments	29467404
Identification Methods	affinity chromatography technology
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	PID~PID
Common GO terms	GO:0001920 - negative regulation of receptor recycling GO:0005112 - Notch binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm and 24 others more... GO:0005938 - cell cortex GO:0007405 - neuroblast proliferation GO:0007406 - negative regulation of neuroblast proliferation GO:0008104 - protein localization GO:0008347 - glial cell migration GO:0009786 - regulation of asymmetric cell division GO:0010629 - negative regulation of gene expression GO:0014019 - neuroblast development GO:0016360 - sensory organ precursor cell fate determination GO:0035050 - embryonic heart tube development GO:0035883 - enteroendocrine cell differentiation GO:0042694 - muscle cell fate specification GO:0045035 - sensory organ precursor cell division GO:0045178 - basal part of cell GO:0045746 - negative regulation of Notch signaling pathway GO:0045807 - positive regulation of endocytosis GO:0050767 - regulation of neurogenesis GO:0050769 - positive regulation of neurogenesis GO:0051642 - centrosome localization GO:0051960 - regulation of nervous system development GO:0055059 - asymmetric neuroblast division GO:0061320 - pericardial nephrocyte differentiation GO:0061382 - Malpighian tubule tip cell differentiation GO:1902692 - regulation of neuroblast proliferation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	556
Dm

1	556

+

Hs

+

Hs

+

Mm

+

Ce

+

Hs

+

Hs

+

Rn

+

Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024