HitPredict

Interactor 1: FER (P16591)
Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)
Gene: FER

Interactor 2: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	20598684
Identification Methods	array technology
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1, SH2~SH3_1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 508
+	Hs
		426965 FES_HUMAN (1-820): 0: 786: 49.94		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		561388 FER_HUMAN (1-822): 0: 934: 100.00		SRC8_HUMAN (291-502): 1.23e-34: 138: 20.72
+	Hs
		337502 ABL1_HUMAN (367-822): 3.93e-158: 492: 33.75		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Mm
		337634 ABL1_MOUSE (367-822): 5.9e-158: 491: 33.75		ABI1_MOUSE (1-508): 1.42e-122: 369: 91.93
+	Hs
		433413 YES_HUMAN (319-816): 7.62e-160: 477: 31.45		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		789078 ABL2_HUMAN (291-822): 9.93e-152: 476: 30.90		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Mm
		70555 B2RQ57_MOUSE (291-822): 7.46e-152: 474: 30.53		ABI1_MOUSE (1-508): 1.42e-122: 369: 91.93
+	Hs
		337572 ABL1_HUMAN (367-822): 3.93e-158: 492: 33.75		ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84
+	Dm
		337662 ABL_DROME (320-822): 2.45e-157: 500: 31.29		Q9Y0S9_DROME (1-504): 2.01e-77: 252: 34.72
+	Hs
		789094 ABL2_HUMAN (291-822): 9.93e-152: 476: 30.90		ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84
+	Hs
		337590 ABL1_HUMAN (367-822): 3.93e-158: 492: 33.75		ASAP1_HUMAN (107-505): 8.23e-33: 135: 16.83
+	Hs
		433350 YES_HUMAN (319-816): 7.62e-160: 477: 31.45		SRC8_HUMAN (291-502): 1.23e-34: 138: 20.72
+	Hs
		789066 ABL2_HUMAN (291-822): 9.93e-152: 476: 30.90		SRC8_HUMAN (291-502): 1.23e-34: 138: 20.72
+	Hs
		166023 ABL1_HUMAN (367-822): 3.93e-158: 492: 33.75		SYNJ2_HUMAN (39-458): 2.1e-26: 115: 13.88
+	Hs
		433354 YES_HUMAN (319-816): 7.62e-160: 477: 31.45		LASP1_HUMAN (285-503): 9.91e-33: 127: 19.28
+	Hs
		235462 ABL1_HUMAN (367-822): 3.93e-158: 492: 33.75		VINEX_HUMAN (229-504): 5.02e-15: 79.8: 15.58
+	Hs
		337608 ABL1_HUMAN (367-822): 3.93e-158: 492: 33.75		CD2AP_HUMAN (451-508): 2.26e-14: 77.9: 40.68
+	Hs
		433551 LYN_HUMAN (372-817): 5.02e-159: 474: 32.26		HCLS1_HUMAN (342-503): 7.7e-19: 91.2: 22.17
+	Hs
		297808 LYN_HUMAN (372-817): 5.02e-159: 474: 32.26		K0754_HUMAN (80-400): 5.9e-17: 86.7: 7.60
+	Hs
		235483 ABL2_HUMAN (291-822): 9.93e-152: 476: 30.90		VINEX_HUMAN (229-504): 5.02e-15: 79.8: 15.58