Protein: TDGF1
Protein Cripto (Cripto, EGF-CFC family member) (Cripto-1 growth factor) (CRGF) (Epidermal growth factor-like cripto protein CR1) (Teratocarcinoma-derived growth factor 1)

Gene: TDGF1, CRIPTO
Organism: Homo sapiens
Interactions: 72
UniProt ID: P13385

Gene Ontology (top 5):
GO:0001568 - blood vessel development
GO:0001763 - morphogenesis of a branching structure
GO:0002042 - cell migration involved in sprouting angiogenesis
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

561369

MAEA
E3 ubiquitin-protein transferase MAEA

4

5

High-throughput

0.691

High

561391

GID8
Glucose-induced degradation protein 8 homolog

4

5

High-throughput

0.691

High

287857

MYCB2
E3 ubiquitin-protein ligase MYCBP2

3

0

High-throughput

0.638

High

561372

ARMC8
Armadillo repeat-containing protein 8

3

0

High-throughput

0.638

High

561381

ZMY19
Zinc finger MYND domain-containing protein 19

3

0

High-throughput

0.638

High

561397

MKLN1
Muskelin

4

1

High-throughput

0.630

High

561386

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

2

2

High-throughput

0.628

High

561384

RANB9
Ran-binding protein 9

2

3

High-throughput

0.611

High

561367

RBP10
Ran-binding protein 10

3

3

High-throughput

0.609

High

561389

RMD5A
E3 ubiquitin-protein transferase RMND5A

3

4

High-throughput

0.609

High

561348

ACV1B
Activin receptor type-1B

2

7

Small-scale

0.602

High

561359

IL18
Interleukin-18

2

0

High-throughput

0.602

High

561387

SIL1
Nucleotide exchange factor SIL1

2

0

High-throughput

0.602

High

561366

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

2

2

High-throughput

0.574

High

561382

RMD5B
E3 ubiquitin-protein transferase RMND5B

2

4

High-throughput

0.574

High

561380

COA7
Cytochrome c oxidase assembly factor 7

2

1

High-throughput

0.549

High

248378

GDF9
Growth/differentiation factor 9

1

11

High-throughput

0.541

High

561343

FBLN1
Fibulin-1

1

4

High-throughput

0.541

High

296338

ATRN
Attractin

1

8

High-throughput

0.536

High

335376

GDF11
Growth/differentiation factor 11

1

8

High-throughput

0.536

High

504701

FBSP1
F-box/SPRY domain-containing protein 1

1

3

High-throughput

0.536

High

561339

CSPG2
Versican core protein

1

2

High-throughput

0.536

High

561342

FGFR4
Fibroblast growth factor receptor 4

1

2

High-throughput

0.536

High

561345

GALNS
N-acetylgalactosamine-6-sulfatase

1

1

High-throughput

0.536

High

561355

SEM3B
Semaphorin-3B

1

3

High-throughput

0.536

High

561356

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

5

High-throughput

0.536

High

561365

METRL
Meteorin-like protein

1

1

High-throughput

0.536

High

561377

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

2

High-throughput

0.536

High

561394

PLXA1
Plexin-A1

1

5

High-throughput

0.536

High

561395

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

5

High-throughput

0.536

High

561396

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

7

High-throughput

0.536

High

561399

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.536

High

397888

ANGI
Angiogenin

1

0

High-throughput

0.518

High

561351

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.518

High

561352

AP2S1
AP-2 complex subunit sigma

1

0

High-throughput

0.518

High

561350

ECE1
Endothelin-converting enzyme 1

1

0

High-throughput

0.513

High

561361

T132A
Transmembrane protein 132A

1

0

High-throughput

0.513

High

561385

NEUR1
Sialidase-1

1

0

High-throughput

0.513

High

483483

INHBB
Inhibin beta B chain

1

9

Small-scale

0.501

High

554142

BMP4
Bone morphogenetic protein 4

1

10

Small-scale

0.501

High

561340

BMP7
Bone morphogenetic protein 7

1

10

Small-scale

0.501

High

561341

BMP6
Bone morphogenetic protein 6

1

10

Small-scale

0.501

High

561344

AVR2A
Activin receptor type-2A

1

7

Small-scale

0.501

High

561347

BMR1A
Bone morphogenetic protein receptor type-1A

1

7

Small-scale

0.501

High

561349

TGFR2
TGF-beta receptor type-2

1

7

Small-scale

0.501

High

561354

ACVR1
Activin receptor type-1

1

7

Small-scale

0.501

High

561357

AVR2B
Activin receptor type-2B

1

7

Small-scale

0.501

High

561358

BMPR2
Bone morphogenetic protein receptor type-2

1

7

Small-scale

0.501

High

561383

NODAL
Nodal homolog

1

12

Small-scale

0.501

High

561390

GDF3
Growth/differentiation factor 3

1

10

Small-scale

0.501

High

561362

OFUT4
GDP-fucose protein O-fucosyltransferase 4

1

1

High-throughput

0.489

High

561370

PLGT3
Protein O-glucosyltransferase 3

1

1

High-throughput

0.489

High

561371

MEGF8
Multiple epidermal growth factor-like domains protein 8

1

9

High-throughput

0.489

High

561374

UBR1
E3 ubiquitin-protein ligase UBR1

1

3

High-throughput

0.489

High

561375

UBR2
E3 ubiquitin-protein ligase UBR2

1

3

High-throughput

0.489

High

561379

SPRY3
SPRY domain-containing protein 3

1

2

High-throughput

0.489

High

561346

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

Small-scale

0.458

High

561353

YPEL5
Protein yippee-like 5

1

0

High-throughput

0.458

High

561364

RIF1
Telomere-associated protein RIF1

1

1

High-throughput

0.457

High

409239

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

1

High-throughput

0.445

High

141982

FCN1
Ficolin-1

1

0

High-throughput

0.426

High

561376

ORML3
ORM1-like protein 3

1

0

High-throughput

0.426

High

124728

AIP
AH receptor-interacting protein

4

0

High-throughput

0.360

High

561373

GID4
Glucose-induced degradation protein 4 homolog

3

0

High-throughput

0.347

High

561388

WDR26
WD repeat-containing protein 26

3

0

High-throughput

0.347

High

561368

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.282

High

561398

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

0

High-throughput

0.282

High

561360

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.279

Low

561378

CHSTE
Carbohydrate sulfotransferase 14

1

0

High-throughput

0.279

Low

561363

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low

561393

TCAL9
Transcription elongation factor A protein-like 9

1

0

High-throughput

0.249

Low

561392

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025