HitPredict

Interactor 1: TUP1 (P16649)
General transcriptional corepressor TUP1 (Flocculation suppressor protein) (Glucose repression regulatory protein TUP1) (Repressor AER2)
Gene: TUP1

Interactor 2: DOA1 (P36037)
Protein DOA1 (Degradation of alpha protein 1) (Ubiquitin fusion degradation protein 3)
Gene: DOA1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	16554755
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 713 Sc			1 715
+	Sc
		630844 NLE1_YEAST (379-711): 9.92e-61: 214: 20.00		NLE1_YEAST (177-534): 5.33e-37: 147: 14.40
+	Hs
		1240442 POC1A_HUMAN (515-712): 8.46e-39: 150: 23.62		POC1B_HUMAN (174-579): 5.58e-52: 189: 13.95
+	Ce
		1274778 SEL10_CAEEL (272-653): 2.89e-63: 223: 20.36		SEL10_CAEEL (255-455): 1.16e-15: 82.7: 10.67
+	Hs
		197071 PRP4_HUMAN (336-603): 3.34e-64: 223: 23.25		SNR40_HUMAN (4-83): 2.88e-13: 73.9: 15.29
+	Hs
		196984 PRP4_HUMAN (336-603): 3.34e-64: 223: 23.25		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Dm
		1358859 WDS_DROME (521-712): 3.89e-46: 169: 24.87		FBXW7_DROME (4-161): 8.39e-29: 125: 21.89
+	Hs
		1281292 FBXW7_HUMAN (551-708): 1.98e-30: 129: 26.42		FBXW7_HUMAN (205-534): 1.17e-40: 160: 14.63
+	Hs
		921751 GBB2_HUMAN (459-708): 1.86e-49: 178: 23.51		NLE1_HUMAN (4-82): 1.98e-19: 93.9: 22.50
+	Hs
		1016312 TBL3_HUMAN (303-705): 2.41e-50: 190: 17.11		SNR40_HUMAN (4-83): 2.88e-13: 73.9: 15.29
+	Hs
		903174 TBL3_HUMAN (303-705): 2.41e-50: 190: 17.11		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Dm
		1358845 WDS_DROME (521-712): 3.89e-46: 169: 24.87		WDS_DROME (2-82): 8.62e-14: 75.4: 11.49
+	Hs
		1346954 NLE1_HUMAN (553-712): 2.91e-36: 144: 26.09		NLE1_HUMAN (4-82): 1.98e-19: 93.9: 22.50
+	Hs
		903551 NLE1_HUMAN (553-712): 2.91e-36: 144: 26.09		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Hs
		903428 SNR40_HUMAN (562-710): 2.51e-32: 130: 24.83		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Hs
		903418 FBXW7_HUMAN (551-708): 1.98e-30: 129: 26.42		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Hs
		903349 WDR5_HUMAN (606-712): 3.54e-21: 97.1: 21.50		WDR5B_HUMAN (300-611): 1.27e-21: 98.5: 9.20
+	Hs
		792949 WDR5_HUMAN (606-712): 3.54e-21: 97.1: 21.50		LIS1_HUMAN (321-592): 1.05e-20: 97: 8.56
+	Hs
		903077 WDR5_HUMAN (606-712): 3.54e-21: 97.1: 21.50		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64