Interactor 1: PFKA1 (P16861)
ATP-dependent 6-phosphofructokinase subunit alpha (EC 2.7.1.11) (ATP-dependent 6-phosphofructokinase) (ATP-PFK) (Phosphofructokinase 1) (Phosphohexokinase)
Gene: PFK1

Interactor 2: PFKA1 (P16861)
ATP-dependent 6-phosphofructokinase subunit alpha (EC 2.7.1.11) (ATP-dependent 6-phosphofructokinase) (ATP-PFK) (Phosphofructokinase 1) (Phosphohexokinase)
Gene: PFK1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.828

The method score is based on:

Property Details
Experiments 18719252, 12051897, unassigned1933
Identification Methods two hybrid, x-ray crystallography, dihydrofolate reductase reconstruction
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PFK~PFK, PFK~Pfk_N
Common GO terms GO:0003872 - 6-phosphofructokinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
and 11 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 987
Sc

1 987
+ Sc
+ Sc
+ Sp
+ At
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Sa
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024