Interactor 1: ATF2 (P16951)
Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (MXBP protein) (cAMP response element-binding protein CRE-BP1)
Gene: ATF2

Interactor 2: MK01 (P63085)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: Mapk1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.613

The method score is based on:

Property Details
Experiments 15192015, 15304344
Identification Methods affinity chromatography technology, enzymatic study, experimental interaction detection
Interaction Type physical association, direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000165 - MAPK cascade
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
and 3 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 487
Mm

1 358
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Sp
+ Sc
+ Sc
+ Hs
+ At
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024