HitPredict

Interactor 1: YBOX3 (P16989)
Y-box-binding protein 3 (Cold shock domain-containing protein A) (DNA-binding protein A) (Single-strand DNA-binding protein NF-GMB)
Gene: YBX3

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 783
+	Hs
		1168961 LN28B_HUMAN (63-314): 9.71e-58: 190: 22.39		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		931438 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1344179 YBOX2_HUMAN (58-366): 4.54e-50: 173: 42.54		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1334544 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Mm
		1225253 LN28A_MOUSE (64-256): 6.42e-42: 147: 27.09		DDX21_MOUSE (2-783): 1.14e-163: 497: 78.00
+	Hs
		73063 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		B4DW97_HUMAN (49-739): 2.42e-138: 427: 58.18
+	Hs
		931311 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		133971 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571395 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		78151 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		B5BUE6_HUMAN (92-620): 7.42e-135: 414: 24.81
+	Hs
		1308874 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1271664 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		134211 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571600 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		563028 YBOX3_HUMAN (1-372): 8.1e-79: 248: 100.00		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757660 LN28B_HUMAN (63-314): 9.71e-58: 190: 22.39		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Hs
		757556 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Ce
		248035 O62213_CAEEL (78-174): 3.53e-44: 153: 73.20		Q9XUW5_CAEEL (166-543): 6.68e-56: 203: 34.66
+	Ec
		465119 CSPA_ECOLI (87-159): 2.01e-34: 123: 41.10		DEAD_ECOLI (185-630): 1.32e-65: 231: 34.28
+	Ce
		106462 G5EDV3_CAEEL (78-235): 2.34e-35: 132: 38.15		Q9XUW5_CAEEL (166-543): 6.68e-56: 203: 34.66