HitPredict

Interactor 1: SEC2 (P17065)
Rab guanine nucleotide exchange factor SEC2 (GDP-GTP exchange factor SEC2)
Gene: SEC2

Interactor 2: YPT32 (P51996)
GTP-binding protein YPT32/YPT11 (Rab GTPase YPT32)
Gene: YPT32

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	1.00	0.888

Property	Details
Experiments	24248333, 12045183, 20493815, 18221262
Identification Methods	pull down, affinity chromatography technology, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ras~Sec2p
Common GO terms	GO:0005829 - cytosol GO:0005935 - cellular bud neck GO:0006887 - exocytosis GO:0006914 - autophagy GO:0015031 - protein transport
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 759 Sc			1 222
+	Sc
		563951 SEC2_YEAST (1-759): 0: 877: 100.00		YPT31_YEAST (1-222): 1.28e-87: 259: 80.72
+	Hs
		914294 RAB3I_HUMAN (4-404): 5.42e-121: 373: 18.20		RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72
+	Hs
		914234 R3GEF_HUMAN (27-399): 8.31e-93: 296: 15.98		RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72
+	Sp
		143570 SEC2_SCHPO (9-217): 1.21e-49: 184: 27.75		YPT3_SCHPO (7-222): 1.68e-89: 264: 61.29