HitPredict

Interactor 1: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Interactor 2: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 776
+	Hs
		713963 HS71L_HUMAN (1-643): 0: 960: 79.32		CUL1_HUMAN (1-776): 0: 911: 100.00
+	Hs
		504040 HSP7C_HUMAN (4-615): 0: 940: 79.25		CUL1_HUMAN (1-776): 0: 911: 100.00
+	Hs
		713966 HS71L_HUMAN (1-643): 0: 960: 79.32		CUL4A_HUMAN (7-776): 0: 781: 30.41
+	Hs
		713967 HS71L_HUMAN (1-643): 0: 960: 79.32		CUL4B_HUMAN (7-776): 0: 773: 29.90
+	Hs
		504043 HSP7C_HUMAN (4-615): 0: 940: 79.25		CUL4A_HUMAN (7-776): 0: 781: 30.41
+	Hs
		504044 HSP7C_HUMAN (4-615): 0: 940: 79.25		CUL4B_HUMAN (7-776): 0: 773: 29.90
+	Hs
		713965 HS71L_HUMAN (1-643): 0: 960: 79.32		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Hs
		504042 HSP7C_HUMAN (4-615): 0: 940: 79.25		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Hs
		713964 HS71L_HUMAN (1-643): 0: 960: 79.32		CUL2_HUMAN (13-776): 0: 720: 35.98
+	Hs
		504041 HSP7C_HUMAN (4-615): 0: 940: 79.25		CUL2_HUMAN (13-776): 0: 720: 35.98
+	Hs
		714040 HS71L_HUMAN (1-643): 0: 960: 79.32		CUL5_HUMAN (2-776): 0: 622: 28.85
+	Hs
		504518 HSP7C_HUMAN (4-615): 0: 940: 79.25		CUL5_HUMAN (2-776): 0: 622: 28.85
+	Sc
		450227 HSP73_YEAST (8-643): 0: 910: 70.59		CDC53_YEAST (13-776): 0: 628: 31.36