HitPredict

Interactor 1: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Interactor 2: POC1A (Q8NBT0)
POC1 centriolar protein homolog A (Pix2) (Proteome of centriole protein 1A) (WD repeat-containing protein 51A)
Gene: POC1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005814 - centriole
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 407
+	Hs
		714020 HS71L_HUMAN (1-643): 0: 960: 79.32		POC1A_HUMAN (1-407): 1.25e-118: 352: 100.00
+	Hs
		504412 HSP7C_HUMAN (4-615): 0: 940: 79.25		POC1A_HUMAN (1-407): 1.25e-118: 352: 100.00
+	Hs
		503614 HSP7C_HUMAN (4-615): 0: 940: 79.25		LIS1_HUMAN (141-406): 2.29e-77: 246: 20.21
+	Hs
		504523 HSP7C_HUMAN (4-615): 0: 940: 79.25		FBXW7_HUMAN (131-406): 1.07e-65: 223: 20.79
+	Hs
		503817 HSP7C_HUMAN (4-615): 0: 940: 79.25		WDR5_HUMAN (259-406): 6.14e-34: 130: 15.44
+	Hs
		564054 HSP76_HUMAN (1-643): 0: 970: 100.00		GBB2_HUMAN (8-131): 4.26e-21: 95.3: 25.98
+	Hs
		504344 HSP7C_HUMAN (4-615): 0: 940: 79.25		WDR5B_HUMAN (259-406): 1.83e-31: 123: 15.44
+	Hs
		503848 HSP7C_HUMAN (4-615): 0: 940: 79.25		GBB2_HUMAN (8-131): 4.26e-21: 95.3: 25.98
+	Hs
		483785 HS71B_HUMAN (5-643): 0: 934: 82.16		GBB2_HUMAN (8-131): 4.26e-21: 95.3: 25.98
+	Hs
		871525 HSP72_HUMAN (3-643): 0: 925: 77.45		GBB2_HUMAN (8-131): 4.26e-21: 95.3: 25.98
+	Sc
		450018 HSP73_YEAST (8-643): 0: 910: 70.59		TAF5_YEAST (7-217): 3.48e-24: 107: 30.19
+	Dm
		505116 HSP7D_DROME (4-614): 0: 923: 79.38		FBXW7_DROME (15-218): 5.9e-18: 88.2: 29.95