HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction GO:1903077 - negative regulation of protein localization to plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 1202
+	Hs
		1025343 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		950961 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		925243 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		893955 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		900430 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		545349 RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		1203019 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		564633 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		925488 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		894274 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		900754 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		724776 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		724757 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		564594 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		725138 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		MYH10_HUMAN (320-813): 7.13e-10: 66: 11.29
+	Hs
		951125 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		725125 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		MYH10_HUMAN (320-813): 7.13e-10: 66: 11.29
+	Hs
		925406 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		894179 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		900650 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62