HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: EHD2 (Q9NZN4)
EH domain-containing protein 2 (PAST homolog 2)
Gene: EHD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0030866 - cortical actin cytoskeleton organization GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 543
+	Hs
		1330957 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		1330916 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Hs
		1328986 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		EHD4_HUMAN (1-543): 0: 795: 67.95
+	Hs
		951410 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		925677 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		894522 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		900984 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		545664 RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		564685 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Hs
		892636 RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		916028 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		436544 RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Hs
		545618 RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Hs
		892597 RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Hs
		915975 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Hs
		925602 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		EHD4_HUMAN (1-543): 0: 795: 67.95
+	Hs
		894411 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		EHD4_HUMAN (1-543): 0: 795: 67.95
+	Hs
		894047 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		ITSN1_HUMAN (444-532): 7.23e-28: 120: 36.67
+	Hs
		915702 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		ITSN1_HUMAN (444-532): 7.23e-28: 120: 36.67