HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0007015 - actin filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 1098
+	Hs
		1330986 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		951455 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		925725 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		894581 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		NEB1_HUMAN (1-1098): 6.8e-118: 392: 100.00
+	Hs
		1021562 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		564636 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		DLG3_HUMAN (311-1098): 1.22e-71: 257: 13.03
+	Hs
		951207 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		DLG3_HUMAN (311-1098): 1.22e-71: 257: 13.03
+	Hs
		564500 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		950954 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		925239 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Hs
		893948 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		DLG1_HUMAN (225-1097): 2.22e-67: 246: 13.80
+	Mm
		925797 RAC1_MOUSE (10-195): 4.15e-80: 238: 63.98		DLG4_MOUSE (376-1098): 3.11e-50: 192: 13.00
+	Mm
		925799 RAC1_MOUSE (10-195): 4.15e-80: 238: 63.98		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Mm
		892727 CDC42_MOUSE (9-193): 1.09e-78: 235: 67.57		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Hs
		894342 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		NEB2_HUMAN (1-826): 1.2e-42: 170: 43.65
+	Hs
		1020215 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		876341 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		AFAD_HUMAN (419-593): 1.96e-23: 110: 30.11
+	Hs
		564499 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		925236 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65
+	Hs
		893945 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		PTN13_HUMAN (2-937): 2.68e-18: 93.5: 11.65