HitPredict

Interactor 1: HMGA1 (P17096)
High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein R)
Gene: HMGA1

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	30021884, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0030527 - structural constituent of chromatin
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 107 Hs			1 126
+	Hs
		564927 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62
+	Hs
		564845 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2BFS_HUMAN (1-126): 1.26e-53: 166: 96.83
+	Hs
		564850 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		564990 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		565015 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B1M_HUMAN (1-126): 5.38e-54: 166: 96.03
+	Hs
		564846 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		565016 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62
+	Hs
		564938 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2B2C_HUMAN (1-96): 1.25e-43: 143: 91.67