Protein: TM9S3
Transmembrane 9 superfamily member 3 (EP70-P-iso) (SM-11044-binding protein)

Gene: TM9S3, TM9SF3
Organism: Homo sapiens
Interactions: 162
UniProt ID: Q9HD45

Gene Ontology (top 5):
GO:0016020 - membrane
GO:0072657 - protein localization to membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1431463

P2Y12
P2Y purinoceptor 12

2

12

High-throughput

0.628

High

1312990

S35F2
Solute carrier family 35 member F2

2

5

High-throughput

0.601

High

1439662

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

2

0

High-throughput

0.576

High

702850

5HT2C
5-hydroxytryptamine receptor 2C

2

3

High-throughput

0.574

High

396997

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

1286917

TM11B
Transmembrane protease serine 11B

2

7

High-throughput

0.558

High

1430963

UN93B
Protein unc-93 homolog B1

2

2

High-throughput

0.549

High

420845

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

4

High-throughput

0.536

High

564401

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

564932

ICAM2
Intercellular adhesion molecule 2

1

2

High-throughput

0.536

High

690392

STOM
Stomatin

1

1

High-throughput

0.536

High

1325926

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

1

High-throughput

0.536

High

1384631

S67A1
Solute carrier family 67 member A1

1

1

High-throughput

0.536

High

1393082

CREL1
Protein disulfide isomerase CRELD1

1

1

High-throughput

0.536

High

1395670

S35E1
Solute carrier family 35 member E1

1

4

High-throughput

0.536

High

1407303

CML1
Chemerin-like receptor 1

1

8

High-throughput

0.536

High

1439667

CLC2D
C-type lectin domain family 2 member D

1

3

High-throughput

0.536

High

243004

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.533

High

1031552

IFM3
Interferon-induced transmembrane protein 3

2

1

High-throughput

0.533

High

401526

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

2

High-throughput

0.521

High

1313848

S15A3
Solute carrier family 15 member 3

2

2

High-throughput

0.521

High

458492

ADRB2
Beta-2 adrenergic receptor

1

5

High-throughput

0.515

High

1412676

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.515

High

423232

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.513

High

699154

CALX
Calnexin

1

0

High-throughput

0.513

High

1336530

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.513

High

1350079

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

139326

UPK2
Uroplakin-2

1

2

High-throughput

0.489

High

349581

TSN15
Tetraspanin-15

1

5

High-throughput

0.489

High

351971

S1PR4
Sphingosine 1-phosphate receptor 4

1

13

High-throughput

0.489

High

638251

S1PR1
Sphingosine 1-phosphate receptor 1

1

12

High-throughput

0.489

High

669253

NK1R
Substance-P receptor

1

6

High-throughput

0.489

High

820587

GPV
Platelet glycoprotein V

1

1

High-throughput

0.489

High

832449

OPRX
Nociceptin receptor

1

4

High-throughput

0.489

High

833874

P2RY2
P2Y purinoceptor 2

1

14

High-throughput

0.489

High

868316

P2RY1
P2Y purinoceptor 1

1

13

High-throughput

0.489

High

1366253

LPAR1
Lysophosphatidic acid receptor 1

1

11

High-throughput

0.489

High

1434644

SG196
Protein O-mannose kinase

1

2

High-throughput

0.489

High

1439660

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

1

High-throughput

0.489

High

48806

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.479

High

174105

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.479

High

363890

EGFR
Epidermal growth factor receptor

1

3

High-throughput

0.479

High

404443

GCR
Glucocorticoid receptor

1

2

High-throughput

0.479

High

786270

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.479

High

955628

CDC42
Cell division control protein 42 homolog

1

4

High-throughput

0.479

High

975262

ARF6
ADP-ribosylation factor 6

1

5

High-throughput

0.479

High

988731

RAC1
Ras-related C3 botulinum toxin substrate 1

1

4

High-throughput

0.479

High

1287451

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

2

High-throughput

0.479

High

1352307

RN128
E3 ubiquitin-protein ligase RNF128

1

3

High-throughput

0.479

High

1383093

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

1418457

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

1439659

TMPS4
Transmembrane protease serine 4

1

7

High-throughput

0.479

High

1439664

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

184325

NPHP1
Nephrocystin-1

1

0

High-throughput

0.458

High

327461

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

346367

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

417774

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

488870

FURIN
Furin

1

0

High-throughput

0.458

High

643084

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

693100

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

774642

BASI
Basigin

1

0

High-throughput

0.458

High

1114364

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1233504

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1309893

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1334948

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1366575

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

710897

EPHB2
Ephrin type-B receptor 2

1

2

High-throughput

0.457

High

1055098

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

3

High-throughput

0.457

High

189995

MOT7
Monocarboxylate transporter 7

1

6

High-throughput

0.445

High

211184

CTR4
Cationic amino acid transporter 4

1

7

High-throughput

0.445

High

256163

S19A2
Thiamine transporter 1

1

3

High-throughput

0.445

High

339052

GTR10
Solute carrier family 2, facilitated glucose transporter member 10

1

2

High-throughput

0.445

High

722628

CTR1
High affinity cationic amino acid transporter 1

1

7

High-throughput

0.445

High

870317

S6A12
Sodium- and chloride-dependent betaine transporter

1

7

High-throughput

0.445

High

870423

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

7

High-throughput

0.445

High

925612

MOT1
Monocarboxylate transporter 1

1

6

High-throughput

0.445

High

1139580

S39AE
Metal cation symporter ZIP14

1

4

High-throughput

0.445

High

1236330

MFSD5
Molybdate-anion transporter

1

2

High-throughput

0.445

High

1420282

S19A3
Thiamine transporter 2

1

3

High-throughput

0.445

High

218807

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.437

High

294362

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

414671

P53
Cellular tumor antigen p53

1

2

High-throughput

0.437

High

425636

ISG15
Ubiquitin-like protein ISG15

1

3

High-throughput

0.437

High

581305

RAC2
Ras-related C3 botulinum toxin substrate 2

1

3

High-throughput

0.437

High

589756

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

696575

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

769243

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

962516

RHOA
Transforming protein RhoA

1

4

High-throughput

0.437

High

978322

RHOB
Rho-related GTP-binding protein RhoB

1

4

High-throughput

0.437

High

1005122

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1107235

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.437

High

1108176

SQSTM
Sequestosome-1

1

1

High-throughput

0.437

High

1142184

P2RY6
P2Y purinoceptor 6

1

13

High-throughput

0.437

High

1151888

RHOH
Rho-related GTP-binding protein RhoH

1

7

High-throughput

0.437

High

1238827

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1249231

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

1255641

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1308217

PLD3
5'-3' exonuclease PLD3

1

5

High-throughput

0.437

High

1385234

PLD4
5'-3' exonuclease PLD4

1

5

High-throughput

0.437

High

1430477

RAB1B
Ras-related protein Rab-1B

1

4

High-throughput

0.437

High

1431212

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

1

High-throughput

0.437

High

1433518

RHOJ
Rho-related GTP-binding protein RhoJ

1

5

High-throughput

0.437

High

1433956

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1438169

RHOF
Rho-related GTP-binding protein RhoF

1

5

High-throughput

0.437

High

1439663

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

1439665

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

880876

NRAM2
Natural resistance-associated macrophage protein 2

1

0

High-throughput

0.426

High

1407399

S29A1
Equilibrative nucleoside transporter 1

1

0

High-throughput

0.426

High

1439661

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

Small-scale

0.426

High

166422

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

3

High-throughput

0.407

High

303289

S22A5
Organic cation/carnitine transporter 2

1

5

High-throughput

0.407

High

652253

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

4

High-throughput

0.407

High

1209687

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.407

High

1229422

S6A19
Sodium-dependent neutral amino acid transporter B(0)AT1

1

7

High-throughput

0.407

High

1242944

S39A4
Zinc transporter ZIP4

1

4

High-throughput

0.407

High

1260509

S35D2
Nucleotide sugar transporter SLC35D2

1

6

High-throughput

0.407

High

1274102

MOT9
Monocarboxylate transporter 9

1

7

High-throughput

0.407

High

1308983

S22A9
Organic anion transporter 7

1

5

High-throughput

0.407

High

1324794

LAT4
Large neutral amino acids transporter small subunit 4

1

3

High-throughput

0.407

High

1335732

MOT11
Monocarboxylate transporter 11

1

6

High-throughput

0.407

High

1337965

ZNT7
Zinc transporter 7

1

3

High-throughput

0.407

High

1348642

S7A14
Solute carrier family 7 member 14

1

7

High-throughput

0.407

High

1361315

CTR3
Cationic amino acid transporter 3

1

7

High-throughput

0.407

High

1439657

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

7

High-throughput

0.407

High

1439668

S22AE
Solute carrier family 22 member 14

1

5

High-throughput

0.407

High

158327

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.279

Low

378653

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.279

Low

583942

KCNE1
Potassium voltage-gated channel subfamily E member 1

1

0

High-throughput

0.279

Low

914482

EFNB2
Ephrin-B2

1

0

High-throughput

0.279

Low

1310434

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1355932

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.279

Low

1370926

FOXJ1
Forkhead box protein J1

1

0

High-throughput

0.279

Low

1439666

FLOWR
Calcium channel flower homolog

1

0

High-throughput

0.279

Low

48082

RBM47
RNA-binding protein 47

1

0

High-throughput

0.249

Low

61761

SBNO1
Protein strawberry notch homolog 1

1

0

High-throughput

0.249

Low

106684

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

164448

NRP1
Neuropilin-1

1

0

High-throughput

0.249

Low

519236

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

580705

AMPN
Aminopeptidase N

1

0

High-throughput

0.249

Low

831468

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

879492

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

971116

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1117852

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.249

Low

1162569

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1163904

DUS7
Dual specificity protein phosphatase 7

1

0

High-throughput

0.249

Low

1203090

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.249

Low

1323003

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

1339187

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

1350642

ZN675
Zinc finger protein 675

1

0

High-throughput

0.249

Low

1381974

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

1384824

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.249

Low

1386374

FAF2
FAS-associated factor 2

1

0

High-throughput

0.249

Low

1397448

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

1412445

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.249

Low

1414671

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.249

Low

1435322

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1436095

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.249

Low

1439658

ANLN
Anillin

1

0

High-throughput

0.249

Low

1133

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

1180323

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.232

Low

1238900

MFS12
Major facilitator superfamily domain-containing protein 12

1

0

High-throughput

0.232

Low

887243

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.213

Low


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Last updated: 11Aug2025