Protein: XPO5
Exportin-5 (Exp5) (Ran-binding protein 21)

Gene: XPO5
Organism: Homo sapiens
Interactions: 184
UniProt ID: Q9HAV4

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005049 - nuclear export signal receptor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

919273

RAN
GTP-binding nuclear protein Ran

2

20

Small-scale

0.831

High

506477

RALB
Ras-related protein Ral-B

2

6

High-throughput

0.726

High

349656

RASH
GTPase HRas

1

3

High-throughput

0.691

High

914368

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.691

High

1216453

RBM45
RNA-binding protein 45

1

7

High-throughput

0.691

High

1019954

ILF3
Interleukin enhancer-binding factor 3

3

6

Small-scale

0.672

High

347933

MYC
Myc proto-oncogene protein

3

11

High-throughput

0.656

High

545171

PVR
Poliovirus receptor

2

1

High-throughput

0.628

High

1048034

RB33A
Ras-related protein Rab-33A

1

1

High-throughput

0.618

High

120650

RHOD
Rho-related GTP-binding protein RhoD

1

18

High-throughput

0.618

High

727318

NU214
Nuclear pore complex protein Nup214

1

17

Small-scale

0.618

High

909144

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.618

High

925631

RAC1
Ras-related C3 botulinum toxin substrate 1

1

10

High-throughput

0.618

High

1334934

RHOF
Rho-related GTP-binding protein RhoF

1

17

High-throughput

0.618

High

1129746

CL12A
C-type lectin domain family 12 member A

3

3

High-throughput

0.609

High

1294594

VSIG2
V-set and immunoglobulin domain-containing protein 2

3

8

High-throughput

0.609

High

999104

EP300
Histone acetyltransferase p300

2

12

High-throughput

0.584

High

1147820

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

9

High-throughput

0.574

High

297680

RHBT1
Rho-related BTB domain-containing protein 1

1

14

High-throughput

0.553

High

1296738

RHOV
Rho-related GTP-binding protein RhoV

1

14

High-throughput

0.553

High

326222

TSN15
Tetraspanin-15

1

1

High-throughput

0.536

High

502566

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.536

High

599014

FPR1
fMet-Leu-Phe receptor

1

20

High-throughput

0.536

High

804346

NOTC1
Neurogenic locus notch homolog protein 1

1

4

High-throughput

0.536

High

818480

SOX2
Transcription factor SOX-2

1

7

High-throughput

0.536

High

1017238

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

High-throughput

0.536

High

1028350

NDK3
Nucleoside diphosphate kinase 3

1

1

High-throughput

0.536

High

1266038

AQP3
Aquaporin-3

1

2

High-throughput

0.536

High

1303764

CDC5L
Cell division cycle 5-like protein

1

2

High-throughput

0.536

High

1334953

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

3

High-throughput

0.536

High

581864

VCAM1
Vascular cell adhesion protein 1

2

2

High-throughput

0.521

High

1202265

LCA5
Lebercilin

2

6

High-throughput

0.521

High

260610

TP4A3
Protein tyrosine phosphatase type IVA 3

1

14

High-throughput

0.515

High

780131

CCNF
Cyclin-F

1

9

High-throughput

0.515

High

795921

MAGA6
Melanoma-associated antigen 6

1

2

High-throughput

0.515

High

1334935

NEK6
Serine/threonine-protein kinase Nek6

1

18

High-throughput

0.515

High

1334954

GSTK1
Glutathione S-transferase kappa 1

1

1

High-throughput

0.515

High

1334957

PHLA3
Pleckstrin homology-like domain family A member 3

1

1

High-throughput

0.515

High

1271965

KLK6
Kallikrein-6

1

4

High-throughput

0.515

High

1083603

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.513

High

1035597

SMAD4
Mothers against decapentaplegic homolog 4

1

6

High-throughput

0.508

High

902759

SUMO2
Small ubiquitin-related modifier 2

1

6

High-throughput

0.501

High

932873

EF1A1
Elongation factor 1-alpha 1

1

8

Small-scale

0.501

High

364442

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.493

High

50250

HACL2
2-hydroxyacyl-CoA lyase 2

1

3

High-throughput

0.489

High

68099

HIDE1
Protein HIDE1

1

1

High-throughput

0.489

High

172231

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.489

High

351194

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

1

High-throughput

0.489

High

435766

IGF1R
Insulin-like growth factor 1 receptor

1

14

High-throughput

0.489

High

626728

EDNRA
Endothelin-1 receptor

1

12

High-throughput

0.489

High

639648

TNR5
Tumor necrosis factor receptor superfamily member 5

1

13

High-throughput

0.489

High

646305

STOM
Stomatin

1

6

High-throughput

0.489

High

664375

AA2BR
Adenosine receptor A2b

1

8

High-throughput

0.489

High

686388

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

8

High-throughput

0.489

High

702300

CD70
CD70 antigen

1

4

High-throughput

0.489

High

723407

APJ
Apelin receptor

1

16

High-throughput

0.489

High

783745

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

8

High-throughput

0.489

High

856468

EFNA4
Ephrin-A4

1

7

High-throughput

0.489

High

876199

PAR2
Proteinase-activated receptor 2

1

20

High-throughput

0.489

High

989755

TNR9
Tumor necrosis factor receptor superfamily member 9

1

13

High-throughput

0.489

High

1031082

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

20

High-throughput

0.489

High

1059506

FXYD3
FXYD domain-containing ion transport regulator 3

1

4

High-throughput

0.489

High

1067620

P2RY6
P2Y purinoceptor 6

1

20

High-throughput

0.489

High

1166228

VSTM1
V-set and transmembrane domain-containing protein 1

1

5

High-throughput

0.489

High

1202556

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

6

High-throughput

0.489

High

1232355

TM130
Transmembrane protein 130

1

1

High-throughput

0.489

High

1233045

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

6

High-throughput

0.489

High

1295703

M4A4A
Membrane-spanning 4-domains subfamily A member 4A

1

3

High-throughput

0.489

High

1299247

OPALI
Opalin

1

5

High-throughput

0.489

High

1328595

UN93B
Protein unc-93 homolog B1

1

5

High-throughput

0.489

High

1334939

GP173
Probable G-protein coupled receptor 173

1

5

High-throughput

0.489

High

1334944

HCST
Hematopoietic cell signal transducer

1

4

High-throughput

0.489

High

1334947

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

2

High-throughput

0.489

High

1334949

ITBP2
Integrin beta-1-binding protein 2

1

2

High-throughput

0.489

High

1334958

GPR45
Probable G-protein coupled receptor 45

1

12

High-throughput

0.489

High

1334959

NPTN
Neuroplastin

1

11

High-throughput

0.489

High

1334951

ZN346
Zinc finger protein 346

1

0

Small-scale

0.480

High

149308

CTRO
Citron Rho-interacting kinase

1

8

High-throughput

0.479

High

165875

KDM6B
Lysine-specific demethylase 6B

1

4

Small-scale

0.479

High

178006

TMPS2
Transmembrane protease serine 2

1

5

High-throughput

0.479

High

179829

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.479

High

228746

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

244958

BRD4
Bromodomain-containing protein 4

1

6

High-throughput

0.479

High

326778

SNAI1
Zinc finger protein SNAI1

1

3

High-throughput

0.479

High

328963

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.479

High

339000

EGFR
Epidermal growth factor receptor

1

13

High-throughput

0.479

High

429941

CATL1
Procathepsin L

1

2

High-throughput

0.479

High

476405

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.479

High

487770

ANDR
Androgen receptor

1

12

High-throughput

0.479

High

546890

PPAP
Prostatic acid phosphatase

1

4

High-throughput

0.479

High

553757

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

568799

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

11

Small-scale

0.479

High

622533

CCND1
G1/S-specific cyclin-D1

1

8

High-throughput

0.479

High

652296

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

685037

STIP1
Stress-induced-phosphoprotein 1

1

8

High-throughput

0.479

High

721487

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

729360

VGFR3
Vascular endothelial growth factor receptor 3

1

10

High-throughput

0.479

High

742541

SYUA
Alpha-synuclein

1

2

High-throughput

0.479

High

824397

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.479

High

834671

NU153
Nuclear pore complex protein Nup153

1

20

Small-scale

0.479

High

855950

ZN131
Zinc finger protein 131

1

1

High-throughput

0.479

High

877901

FOXA1
Hepatocyte nuclear factor 3-alpha

1

7

High-throughput

0.479

High

913122

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.479

High

922400

RL31
Large ribosomal subunit protein eL31

1

3

High-throughput

0.479

High

941447

RNF4
E3 ubiquitin-protein ligase RNF4

1

6

High-throughput

0.479

High

943805

CCNA1
Cyclin-A1

1

4

High-throughput

0.479

High

1026652

FADD
FAS-associated death domain protein

1

2

Small-scale

0.479

High

1030647

CLN3
Battenin

1

3

Small-scale

0.479

High

1036095

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1042573

CUL3
Cullin-3

1

8

High-throughput

0.479

High

1050270

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

7

High-throughput

0.479

High

1062200

HAPR1
HUWE1-associated protein modifying stress responses 1

1

2

High-throughput

0.479

High

1077343

T22D1
TSC22 domain family protein 1

1

6

High-throughput

0.479

High

1085688

HIF1A
Hypoxia-inducible factor 1-alpha

1

6

High-throughput

0.479

High

1088240

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

18

High-throughput

0.479

High

1148792

VIR
Protein virilizer homolog

1

5

High-throughput

0.479

High

1171777

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

1184344

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.479

High

1188887

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.479

High

1199694

ZN598
E3 ubiquitin-protein ligase ZNF598

1

10

High-throughput

0.479

High

1206059

MIB1
E3 ubiquitin-protein ligase MIB1

1

7

High-throughput

0.479

High

1220821

ASXL1
Polycomb group protein ASXL1

1

3

High-throughput

0.479

High

1267167

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1269657

ESR2
Estrogen receptor beta

1

12

High-throughput

0.479

High

1273076

FUBP2
Far upstream element-binding protein 2

1

5

Small-scale

0.479

High

1294019

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.479

High

1302763

RUFY1
RUN and FYVE domain-containing protein 1

1

7

High-throughput

0.479

High

1302988

MMS19
MMS19 nucleotide excision repair protein homolog

1

2

High-throughput

0.479

High

1326158

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

1

High-throughput

0.479

High

1331330

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1334936

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

8

High-throughput

0.479

High

1334940

RAD18
E3 ubiquitin-protein ligase RAD18

1

3

High-throughput

0.479

High

1334941

TLS1
Splicing factor C9orf78

1

4

High-throughput

0.479

High

1334943

ANFY1
Rabankyrin-5

1

5

High-throughput

0.479

High

1334946

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

1334948

MRT4
mRNA turnover protein 4 homolog

1

3

Small-scale

0.479

High

1334950

NUP50
Nuclear pore complex protein Nup50

1

16

High-throughput

0.479

High

1334955

ZN330
Zinc finger protein 330

1

3

High-throughput

0.479

High

1334956

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.479

High

1334960

NEMO
NF-kappa-B essential modulator

1

5

High-throughput

0.479

High

637294

CATS
Cathepsin S

1

2

High-throughput

0.470

High

1198177

TM11B
Transmembrane protease serine 11B

1

5

High-throughput

0.470

High

210291

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

1193183

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

665529

EPHA8
Ephrin type-A receptor 8

1

5

High-throughput

0.457

High

321210

PTBP3
Polypyrimidine tract-binding protein 3

1

7

High-throughput

0.445

High

529740

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.445

High

1334937

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

363303

FINC
Fibronectin

1

2

High-throughput

0.437

High

385544

NTRK1
High affinity nerve growth factor receptor

1

12

High-throughput

0.437

High

431277

CATB
Cathepsin B

1

3

High-throughput

0.437

High

530752

ITA4
Integrin alpha-4

1

2

High-throughput

0.437

High

572684

VGFR1
Vascular endothelial growth factor receptor 1

1

10

High-throughput

0.437

High

577067

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

13

High-throughput

0.437

High

591416

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

13

High-throughput

0.437

High

648889

DPP4
Dipeptidyl peptidase 4

1

3

High-throughput

0.437

High

738271

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

10

High-throughput

0.437

High

1087615

CAH9
Carbonic anhydrase 9

1

6

Small-scale

0.437

High

1124458

TM41B
Transmembrane protein 41B

1

2

High-throughput

0.437

High

1165964

LMBRL
Protein LMBR1L

1

6

High-throughput

0.437

High

1166872

LRC31
Leucine-rich repeat-containing protein 31

1

1

High-throughput

0.437

High

1219446

LMTK2
Serine/threonine-protein kinase LMTK2

1

18

High-throughput

0.437

High

1236997

EMC1
ER membrane protein complex subunit 1

1

2

High-throughput

0.437

High

1263907

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

1316754

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.437

High

1334938

TMPS4
Transmembrane protease serine 4

1

5

High-throughput

0.437

High

1334945

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

13

High-throughput

0.437

High

1334952

CLC4E
C-type lectin domain family 4 member E

1

2

High-throughput

0.437

High

831700

CEBPA
CCAAT/enhancer-binding protein alpha

1

7

High-throughput

0.408

High

1132

SIM26
Small integral membrane protein 26

1

5

High-throughput

0.407

High

397670

IPSP
Plasma serine protease inhibitor

1

1

Small-scale

0.407

High

1155806

AR26L
Putative ankyrin repeat domain-containing protein 26-like protein

1

7

High-throughput

0.407

High

1241627

MOT11
Monocarboxylate transporter 11

1

6

High-throughput

0.407

High

156717

TR13B
Tumor necrosis factor receptor superfamily member 13B

1

0

High-throughput

0.279

Low

307663

STBD1
Starch-binding domain-containing protein 1

1

0

High-throughput

0.279

Low

875508

IOD3
Thyroxine 5-deiodinase

1

0

High-throughput

0.279

Low

957484

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

1022355

TSN31
Tetraspanin-31

1

0

High-throughput

0.279

Low

1128405

KRBX4
KRAB domain-containing protein 4

1

0

High-throughput

0.279

Low

1203270

AMGO1
Amphoterin-induced protein 1

1

0

High-throughput

0.279

Low

1329167

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.279

Low

1334942

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.279

Low

1038104

SERC3
Serine incorporator 3

1

0

High-throughput

0.269

Low

1233960

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024