HitPredict

Interactor 1: HMGA1 (P17096)
High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein R)
Gene: HMGA1

Interactor 2: H2A2B (Q8IUE6)
Histone H2A type 2-B (H2A-clustered histone 21)
Gene: H2AC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.671

Property	Details
Experiments	30021884, 33961781, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 107 Hs			1 130
+	Hs
		391537 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		470258 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		564939 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A2A_HUMAN (1-130): 5.07e-68: 202: 94.62
+	Hs
		564989 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A1C_HUMAN (1-130): 5.24e-68: 202: 95.39
+	Hs
		564997 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2A1H_HUMAN (1-128): 7.7e-68: 202: 95.31
+	Hs
		555282 HMGA1_HUMAN (1-107): 5.75e-40: 130: 100.00		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94