Protein: ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 7.2.2.10) (Calcium ATPase at 60A) (Calcium pump) (Sarcoplasmic/endoplasmic reticulum Ca(2+)-ATPase)

Gene: ATC1, SERCA
Organism: Drosophila melanogaster
Interactions: 163
UniProt ID: P22700

Gene Ontology (top 5):
GO:0005388 - P-type calcium transporter activity
GO:0005524 - ATP binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006874 - intracellular calcium ion homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

564948

ATNA
Sodium/potassium-transporting ATPase subunit alpha

2

13

High-throughput

0.737

High

652126

Q9VXG0
Cell division cycle 50, isoform A

2

1

High-throughput

0.737

High

652098

Q9VK06
Phospholipid-transporting ATPase

1

13

High-throughput

0.618

High

197043

O18332
FI01544p

2

6

High-throughput

0.571

High

197926

SURF4
Surfeit locus protein 4 homolog

2

2

High-throughput

0.571

High

304182

ERD2
ER lumen protein-retaining receptor

2

5

High-throughput

0.571

High

432169

MYSA
Myosin heavy chain, muscle

2

1

High-throughput

0.571

High

652005

ATPA
ATP synthase subunit alpha, mitochondrial

2

4

High-throughput

0.571

High

652008

TCPG
T-complex protein 1 subunit gamma

2

5

High-throughput

0.571

High

652021

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

2

2

High-throughput

0.571

High

652024

DX39B
ATP-dependent RNA helicase WM6

2

2

High-throughput

0.571

High

652025

VATA2
V-type proton ATPase catalytic subunit A isoform 2

2

7

High-throughput

0.571

High

652033

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

4

High-throughput

0.571

High

652042

Q7KLX3
Translocon-associated protein subunit delta

2

1

High-throughput

0.571

High

652043

Q7KMQ0
26S proteasome regulatory subunit 7

2

9

High-throughput

0.571

High

652055

Q8STG9
DSec61alpha

2

2

High-throughput

0.571

High

652064

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

2

3

High-throughput

0.571

High

652069

RAB5
Ras-related protein Rab5

2

12

High-throughput

0.571

High

652076

KRH2
Krueppel homolog 2

2

1

High-throughput

0.571

High

652078

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

2

3

High-throughput

0.571

High

652082

Q9VAL7
Calnexin 99A, isoform A

2

7

High-throughput

0.571

High

652085

Q9VAY2
Heat shock protein 83

2

6

High-throughput

0.571

High

652086

Q9VBU5
3-dehydrosphinganine reductase

2

5

High-throughput

0.571

High

652091

Q9VFV9
DnaJ-like-2, isoform A

2

1

High-throughput

0.571

High

652095

ARL8
ADP-ribosylation factor-like protein 8

2

11

High-throughput

0.571

High

652101

NFS1
Cysteine desulfurase, mitochondrial

2

1

High-throughput

0.571

High

652118

Q9VUZ0
Translocon-associated protein subunit beta

2

1

High-throughput

0.571

High

652120

Q9VV75
AT02348p

2

3

High-throughput

0.571

High

652129

Q9VXQ5
Chaperonin containing TCP1 subunit 6

2

1

High-throughput

0.571

High

652131

Q9VZL3
very-long-chain enoyl-CoA reductase

2

1

High-throughput

0.571

High

652135

Q9W3N1
RH59310p

2

6

High-throughput

0.571

High

652027

Q4QQB9
LP21121p

2

0

High-throughput

0.547

High

652050

Q8IPV3
Uncharacterized protein, isoform A

2

0

High-throughput

0.547

High

652097

Q9VJD1
Glucosidase 2 subunit beta

2

0

High-throughput

0.547

High

53634

A1Z823
PRA1 family protein

1

5

High-throughput

0.541

High

652052

CASP8
Caspase-8

2

1

Small-scale

0.533

High

360513

COX2
Cytochrome c oxidase subunit 2

2

1

High-throughput

0.521

High

482728

TPM2
Tropomyosin-2

2

1

High-throughput

0.521

High

652003

CLH
Clathrin heavy chain

2

3

High-throughput

0.521

High

652006

MYSP2
Paramyosin, short form

2

3

High-throughput

0.521

High

652007

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

2

2

High-throughput

0.521

High

652011

ARF1
ADP-ribosylation factor 1

2

5

High-throughput

0.521

High

652038

Q7K485
Cathepsin D

2

1

High-throughput

0.521

High

652044

Q7KN94
Electron transfer flavoprotein subunit alpha

2

1

High-throughput

0.521

High

652059

VDAC
Voltage-dependent anion-selective channel

2

3

High-throughput

0.521

High

652063

FAXC
Failed axon connections

2

1

High-throughput

0.521

High

652079

Q9V9Q4
LD43819p

2

2

High-throughput

0.521

High

652093

IPO9
Importin-9

2

3

High-throughput

0.521

High

652107

Q9VN44
FI07923p

2

5

High-throughput

0.521

High

652111

Q9VQL7
Fatty acid synthase

2

3

High-throughput

0.521

High

652114

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

2

1

High-throughput

0.521

High

652125

Q9VWL0
Mec2

2

7

High-throughput

0.521

High

652051

Q8IR26
RING-type E3 ubiquitin transferase

1

4

High-throughput

0.508

High

87072

SLCB
Sarcolamban B

1

0

Small-scale

0.493

High

87073

SLCA
Sarcolamban A

1

0

Small-scale

0.493

High

387031

ACT4
Actin, larval muscle

1

0

High-throughput

0.486

High

652138

Q9XZ68
Geranylgeranyl transferase type-2 subunit beta

1

0

High-throughput

0.486

High

652128

Q9VXP1
RING-type E3 ubiquitin transferase

1

7

High-throughput

0.481

High

52637

A1Z729
NADP-retinol dehydrogenase

1

8

High-throughput

0.479

High

94120

D5AEK7
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform E

1

6

High-throughput

0.479

High

197208

RAB6
Ras-related protein Rab6

1

12

High-throughput

0.479

High

391874

HSP83
Heat shock protein 83

1

6

High-throughput

0.479

High

541182

KRAF1
Raf homolog serine/threonine-protein kinase Raf

1

6

High-throughput

0.479

High

652002

DDX6
ATP-dependent RNA helicase me31b

1

2

High-throughput

0.479

High

652013

ATPB
ATP synthase subunit beta, mitochondrial

1

4

High-throughput

0.479

High

652018

Q24171
AT08303p

1

6

High-throughput

0.479

High

652022

DSOR1
Dual specificity mitogen-activated protein kinase kinase dSOR1

1

7

High-throughput

0.479

High

652029

Q6NP72
GEO09659p1

1

1

High-throughput

0.479

High

652031

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

5

High-throughput

0.479

High

652032

Q7JYX2
NADP-retinol dehydrogenase

1

8

High-throughput

0.479

High

652034

JAGN
Protein jagunal

1

1

High-throughput

0.479

High

652035

Q7K3H0
LD28067p

1

2

High-throughput

0.479

High

652037

Q7K3K5
LD22804p

1

4

High-throughput

0.479

High

652039

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

1

High-throughput

0.479

High

652040

Q7K4Y0
Desaturase 1, isoform A

1

3

High-throughput

0.479

High

652045

Q7KN97
Pyruvate carboxylase

1

3

High-throughput

0.479

High

652047

Q7KTD0
ABC-type glutathione-S-conjugate transporter

1

4

High-throughput

0.479

High

652049

AKT1
RAC serine/threonine-protein kinase

1

4

High-throughput

0.479

High

652054

Q8MZG9
NADP-retinol dehydrogenase

1

8

High-throughput

0.479

High

652057

HIPPO
Serine/threonine-protein kinase hippo

1

3

High-throughput

0.479

High

652062

MOB1
MOB kinase activator-like 1

1

1

High-throughput

0.479

High

652066

Q961H2
GH23453p

1

2

High-throughput

0.479

High

652067

PGPLC
Peptidoglycan-recognition protein LC

1

1

High-throughput

0.479

High

652080

WARTS
Serine/threonine-protein kinase Warts

1

5

High-throughput

0.479

High

652087

Q9VBU6
Protein RER1

1

3

High-throughput

0.479

High

652090

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

3

High-throughput

0.479

High

652106

Q9VMW2
Reticulon-like protein

1

5

High-throughput

0.479

High

652133

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

8

High-throughput

0.479

High

652023

Q24404
LP10995p

1

1

High-throughput

0.464

High

652084

Q9VAW8
GH09231p

1

1

High-throughput

0.464

High

652134

Q9W316
Carbonic anhydrase-related protein B, isoform A

1

3

High-throughput

0.464

High

652070

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.458

High

652072

BSCL2
Seipin

1

0

Small-scale

0.458

High

53666

A1Z843
Nodal modulator 3

1

3

High-throughput

0.445

High

355915

O96692
small monomeric GTPase

1

12

High-throughput

0.445

High

652009

KARG
Arginine kinase 1

1

1

High-throughput

0.445

High

652015

Q0E9E2
Pyruvate carboxylase

1

3

High-throughput

0.445

High

652036

Q7K3J0
T-complex protein 1 subunit theta

1

4

High-throughput

0.445

High

652056

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.445

High

652065

Q960C7
NADP-retinol dehydrogenase

1

8

High-throughput

0.445

High

652071

Q9V3V6
26S proteasome regulatory complex subunit p50

1

12

High-throughput

0.445

High

652081

Q9VAH7
N-terminal kinase-like protein

1

1

High-throughput

0.445

High

652094

Q9VHL2
T-complex protein 1 subunit eta

1

3

High-throughput

0.445

High

652100

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

4

High-throughput

0.445

High

652103

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

1

High-throughput

0.445

High

652105

Q9VMV9
Reticulon-like protein

1

5

High-throughput

0.445

High

652119

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

6

High-throughput

0.445

High

652132

Q9W0E4
Aminopeptidase

1

2

High-throughput

0.445

High

652136

Q9W414
Regulatory particle triple-A ATPase 4

1

9

High-throughput

0.445

High

652026

SETB1
Histone-lysine N-methyltransferase eggless

1

1

Small-scale

0.439

High

51891

PO210
Nuclear pore membrane glycoprotein 210

1

1

High-throughput

0.437

High

68887

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

1

High-throughput

0.437

High

197136

RAB2
Ras-related protein Rab-2

1

8

High-throughput

0.437

High

473544

RAP1
Ras-related protein Rap1

1

14

High-throughput

0.437

High

652012

CCD1P
Probable cytochrome P450 12d1 proximal, mitochondrial

1

2

High-throughput

0.437

High

652014

Q0E8E8
Phosphate carrier protein, mitochondrial

1

3

High-throughput

0.437

High

652019

DS
Protein dachsous

1

5

High-throughput

0.437

High

652020

DIAP2
Death-associated inhibitor of apoptosis 2

1

4

High-throughput

0.437

High

652058

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

6

High-throughput

0.437

High

652061

CATL1
Cathepsin L1

1

2

High-throughput

0.437

High

652089

Q9VEV3
Tetratricopeptide repeat protein 1

1

3

High-throughput

0.437

High

652127

PGPLE
Peptidoglycan-recognition protein LE

1

1

High-throughput

0.437

High

652075

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

652113

Q9VS47
Lysosomal dipeptide transporter MFSD1

1

0

High-throughput

0.426

High

652115

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.426

High

2700

A0A0B4LFU9
Anastral spindle 2, isoform B

1

1

High-throughput

0.407

High

446265

MLC1
Myosin light chain alkali

1

3

High-throughput

0.407

High

652028

Q6NP35
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

5

High-throughput

0.407

High

652046

CCD1D
Probable cytochrome P450 12d1 distal, mitochondrial

1

3

High-throughput

0.407

High

652073

Q9V3Z4
GH11341p

1

2

High-throughput

0.407

High

652077

Q9V455
Importin subunit alpha

1

1

High-throughput

0.407

High

652096

Q9VI53
LD44267p

1

1

High-throughput

0.407

High

652099

Q9VK46
Protein YIPF

1

3

High-throughput

0.407

High

652102

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

2

High-throughput

0.407

High

652108

CATF
Cathepsin F

1

2

High-throughput

0.407

High

652116

FRL
Formin-like protein

1

2

High-throughput

0.407

High

652121

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

2

High-throughput

0.407

High

652124

Q9VWI2
N(Alpha)-acetyltransferase 15/16, isoform A

1

1

High-throughput

0.407

High

144853

ATPG
ATP synthase subunit gamma, mitochondrial

2

0

High-throughput

0.298

High

652060

LDH
L-lactate dehydrogenase

2

0

High-throughput

0.298

High

652083

Q9VAW3
glutamine--fructose-6-phosphate transaminase

2

0

High-throughput

0.298

High

652123

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

2

0

High-throughput

0.298

High

652137

QCR9
Cytochrome b-c1 complex subunit 9

2

0

High-throughput

0.298

High

652004

FAS2
Fasciclin-2

1

0

High-throughput

0.279

Low

652130

COMDA
COMM domain-containing protein 10 homolog Vlet

1

0

High-throughput

0.265

Low

118725

M9NFG3
THADA, isoform C

1

0

Small-scale

0.249

Low

652010

FOJO
Extracellular serine/threonine protein kinase four-jointed

1

0

High-throughput

0.249

Low

652017

SIMA
Protein similar

1

0

High-throughput

0.249

Low

652030

Q6NQZ7
LD40663p

1

0

High-throughput

0.249

Low

652041

IMD
Protein immune deficiency

1

0

High-throughput

0.249

Low

652068

FADD
Fas-associated death domain protein

1

0

High-throughput

0.249

Low

652088

Q9VCF8
LD23561p

1

0

High-throughput

0.249

Low

652109

Q9VPR1
GH02075p

1

0

High-throughput

0.249

Low

652112

Q9VQS4
Spindly

1

0

High-throughput

0.249

Low

652117

Q9VUK7
RE36140p

1

0

Small-scale

0.249

Low

652122

RS10B
Small ribosomal subunit protein eS10B

1

0

High-throughput

0.249

Low

652053

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

High-throughput

0.238

Low

652016

Q0KIB3
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.232

Low

652048

Q8I062
GH23305p

1

0

High-throughput

0.232

Low

652074

API5
Apoptosis inhibitor 5 homolog

1

0

High-throughput

0.232

Low

652092

ELP6
Elongator complex protein 6

1

0

High-throughput

0.232

Low

652104

Q9VM57
Septin interacting protein 2, isoform A

1

0

High-throughput

0.232

Low

652110

Q9VQI5
Interferon-related developmental regulator 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025