HitPredict

Interactor 1: PHO85 (P17157)
Cyclin-dependent protein kinase PHO85 (EC 2.7.11.22) (Negative regulator of the PHO system) (Serine/threonine-protein kinase PHO85)
Gene: PHO85

Interactor 2: RHO3 (Q00245)
GTP-binding protein RHO3
Gene: RHO3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	16319894
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 305 Sc			1 231
+	Hs
		436162 CDK2_HUMAN (4-303): 7.49e-145: 410: 54.82		RHOC_HUMAN (15-231): 1.07e-88: 261: 46.08
+	Hs
		625333 CDK2_HUMAN (4-303): 7.49e-145: 410: 54.82		RAC1_HUMAN (17-231): 5.6e-78: 234: 40.00
+	Hs
		925197 CDK5_HUMAN (4-303): 1.72e-131: 377: 54.31		RAC1_HUMAN (17-231): 5.6e-78: 234: 40.00
+	Hs
		545324 CDK5_HUMAN (4-303): 1.72e-131: 377: 54.31		RAC2_HUMAN (17-231): 3.86e-74: 224: 38.61
+	Hs
		900381 CDK5_HUMAN (4-303): 1.72e-131: 377: 54.31		RHOA_HUMAN (18-231): 3.81e-74: 224: 46.26
+	Hs
		950926 CDK5_HUMAN (4-303): 1.72e-131: 377: 54.31		RHOG_HUMAN (16-231): 1.01e-73: 223: 41.20
+	Hs
		892319 CDK5_HUMAN (4-303): 1.72e-131: 377: 54.31		RAC3_HUMAN (17-211): 3.31e-73: 222: 41.54
+	Hs
		915609 CDK5_HUMAN (4-303): 1.72e-131: 377: 54.31		RHOB_HUMAN (15-211): 5.46e-61: 191: 49.75
+	Hs
		915610 CDK16_HUMAN (7-297): 3.3e-125: 368: 54.64		RHOB_HUMAN (15-211): 5.46e-61: 191: 49.75
+	Hs
		960334 CDK5_HUMAN (4-303): 1.72e-131: 377: 54.31		RHOF_HUMAN (16-213): 8.3e-53: 171: 42.42
+	Hs
		120390 CDK5_HUMAN (4-303): 1.72e-131: 377: 54.31		RHOD_HUMAN (18-213): 3.34e-52: 169: 40.82