HitPredict

Interactor 1: INAR1 (P17181)
Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Cytokine receptor class-II member 1) (Cytokine receptor family 2 member 1) (CRF2-1) (Type I interferon receptor 1)
Gene: IFNAR1

Interactor 2: PTPRS (Q13332)
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)
Gene: PTPRS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 557 Hs			1 1948
+	Hs
		1031996 I20RB_HUMAN (3-229): 6.07e-42: 154: 17.65		PTPRS_HUMAN (1-1948): 0: 1690: 100.00
+	Hs
		489957 PTPRF_HUMAN (99-540): 1.91e-25: 113: 11.31		PTPRS_HUMAN (1-1948): 0: 1690: 100.00
+	Hs
		616971 PTPRD_HUMAN (99-452): 1.67e-23: 107: 14.68		PTPRS_HUMAN (1-1948): 0: 1690: 100.00
+	Hs
		490004 I22R2_HUMAN (223-430): 6.42e-44: 158: 19.26		PTPRF_HUMAN (1-1948): 0: 1528: 65.42
+	Hs
		489978 I20RB_HUMAN (3-229): 6.07e-42: 154: 17.65		PTPRF_HUMAN (1-1948): 0: 1528: 65.42
+	Hs
		489886 PTPRF_HUMAN (99-540): 1.91e-25: 113: 11.31		PTPRF_HUMAN (1-1948): 0: 1528: 65.42
+	Mm
		574004 NCHL1_MOUSE (2-540): 8.68e-29: 123: 12.08		PTPRA_MOUSE (1168-1948): 0: 802: 37.59
+	Mm
		56906 PTPRF_MOUSE (99-540): 4.67e-25: 112: 12.20		PTPRA_MOUSE (1168-1948): 0: 802: 37.59
+	Mm
		574008 PTPRD_MOUSE (99-545): 6.59e-24: 108: 14.10		PTPRA_MOUSE (1168-1948): 0: 802: 37.59
+	Mm
		828098 PTPRD_MOUSE (99-545): 6.59e-24: 108: 14.10		PTPRE_MOUSE (1350-1948): 0: 762: 46.71
+	Dm
		53797 A1Z921_DROME (21-430): 6.11e-35: 142: 14.45		LAR_DROME (22-1393): 1.24e-173: 583: 31.36
+	Dm
		561767 LAR_DROME (89-527): 3.63e-26: 116: 12.78		LAR_DROME (22-1393): 1.24e-173: 583: 31.36
+	Hs
		617031 I20RA_HUMAN (18-268): 6.6e-50: 182: 20.08		PTPRD_HUMAN (4-1463): 1.86e-106: 381: 16.51
+	Mm
		1112510 SDK1_MOUSE (4-552): 1.22e-34: 141: 11.35		SDK1_MOUSE (30-1155): 5.98e-106: 380: 18.93
+	Hs
		616939 PTPRD_HUMAN (99-452): 1.67e-23: 107: 14.68		PTPRD_HUMAN (4-1463): 1.86e-106: 381: 16.51
+	Hs
		616927 NRCAM_HUMAN (6-488): 7.46e-44: 169: 13.60		PTPRB_HUMAN (257-1309): 2.07e-37: 157: 12.51
+	Hs
		489902 PTPRF_HUMAN (99-540): 1.91e-25: 113: 11.31		PTPRZ_HUMAN (1387-1668): 4.97e-47: 189: 27.21
+	Hs
		616916 PTPRS_HUMAN (99-440): 2.42e-22: 103: 13.22		PTPRB_HUMAN (257-1309): 2.07e-37: 157: 12.51