HitPredict

Interactor 1: KPCA (P17252)
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene: PRKCA

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	10433554
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 672 Hs			1 247
+	Hs
		408587 KPCB_HUMAN (1-664): 0: 749: 78.89		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		566348 KPCA_HUMAN (1-672): 0: 794: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		397155 KPCG_HUMAN (1-670): 0: 706: 68.94		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		566293 KPCA_HUMAN (1-672): 0: 794: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		397154 KPCG_HUMAN (1-670): 0: 706: 68.94		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		909458 KPCE_HUMAN (8-664): 0: 635: 44.61		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		904456 KPCE_HUMAN (8-664): 0: 635: 44.61		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		397138 KPCG_HUMAN (1-670): 0: 706: 68.94		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Mm
		554936 KPCE_MOUSE (8-664): 0: 637: 44.76		1433B_MOUSE (2-247): 8.57e-109: 315: 75.81
+	Hs
		683276 KPCE_HUMAN (8-664): 0: 635: 44.61		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		926942 KPCE_HUMAN (8-664): 0: 635: 44.61		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646812 KPCE_HUMAN (8-664): 0: 635: 44.61		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683974 KPCE_HUMAN (8-664): 0: 635: 44.61		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		681770 AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		681766 AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		681776 AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		116995 SGK1_HUMAN (255-661): 1.16e-153: 452: 38.85		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		116972 SGK1_HUMAN (255-661): 1.16e-153: 452: 38.85		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		681682 AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		683287 KPCD_HUMAN (9-167): 3.67e-57: 207: 39.65		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40