HitPredict

Interactor 1: ITA2 (P17301)
Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b)
Gene: ITGA2

Interactor 2: BTNL8 (Q6UX41)
Butyrophilin-like protein 8
Gene: BTNL8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	V-set~VWA
Common GO terms	GO:0005886 - plasma membrane GO:0009897 - external side of plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1181 Hs			1 500
+	Hs
		566909 ITA2_HUMAN (1-1181): 0: 1250: 100.00		BTNL2_HUMAN (4-225): 3.46e-62: 212: 34.22
+	Hs
		613259 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		BTNL8_HUMAN (17-500): 1.19e-130: 390: 100.00
+	Hs
		1044828 ITA7_HUMAN (5-512): 4.56e-57: 218: 17.52		BTNL8_HUMAN (17-500): 1.19e-130: 390: 100.00
+	Hs
		864308 ITA8_HUMAN (2-546): 1.48e-53: 206: 17.24		BTNL8_HUMAN (17-500): 1.19e-130: 390: 100.00
+	Hs
		530688 ITA4_HUMAN (2-513): 1.18e-52: 203: 20.73		BTNL8_HUMAN (17-500): 1.19e-130: 390: 100.00
+	Hs
		613260 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		BTNL3_HUMAN (1-463): 2.35e-119: 360: 73.92
+	Hs
		443085 ITA5_HUMAN (27-512): 7.68e-47: 185: 15.07		BTNL3_HUMAN (1-463): 2.35e-119: 360: 73.92
+	Hs
		613294 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		BTNL2_HUMAN (4-225): 3.46e-62: 212: 34.22
+	Hs
		1044855 ITA7_HUMAN (5-512): 4.56e-57: 218: 17.52		BTNL2_HUMAN (4-225): 3.46e-62: 212: 34.22
+	Hs
		419246 ITAV_HUMAN (27-513): 6.67e-48: 188: 15.25		BTNL2_HUMAN (4-225): 3.46e-62: 212: 34.22
+	Hs
		443109 ITA5_HUMAN (27-512): 7.68e-47: 185: 15.07		BTNL2_HUMAN (4-225): 3.46e-62: 212: 34.22