HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0007165 - signal transduction
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 196
+	Hs
		566998 CXA1_HUMAN (1-382): 0: 545: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		566992 CXA1_HUMAN (1-382): 0: 545: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		545196 CXA1_HUMAN (1-382): 0: 545: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436147 CXA1_HUMAN (1-382): 0: 545: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		567008 CXA1_HUMAN (1-382): 0: 545: 100.00		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		566989 CXA1_HUMAN (1-382): 0: 545: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		566990 CXA1_HUMAN (1-382): 0: 545: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		564408 CXA1_HUMAN (1-382): 0: 545: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		734406 CXG1_HUMAN (4-373): 1.81e-130: 381: 32.49		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67