HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol and 1 others more... GO:0005925 - focal adhesion
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 7570
+	Hs
		974109 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		DYST_HUMAN (1-7570): 0: 2600: 100.00
+	Rn
		435438 CXA1_RAT (1-382): 0: 546: 97.64		ACTN1_RAT (3770-4283): 1.52e-26: 122: 10.00
+	Hs
		521462 CXA1_HUMAN (1-382): 0: 545: 100.00		ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00
+	Hs
		567012 CXA1_HUMAN (1-382): 0: 545: 100.00		SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95
+	Hs
		567331 CXA1_HUMAN (1-382): 0: 545: 100.00		MACF1_HUMAN (351-1936): 4.95e-21: 105: 11.05
+	Hs
		566963 CXA1_HUMAN (1-382): 0: 545: 100.00		UTRN_HUMAN (264-1530): 1.26e-14: 84.8: 9.65
+	Hs
		567050 CXA1_HUMAN (1-382): 0: 545: 100.00		SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42
+	Hs
		567199 CXA1_HUMAN (1-382): 0: 545: 100.00		SYNE2_HUMAN (282-1774): 1.65e-12: 77.9: 8.82
+	Hs
		567061 CXA1_HUMAN (1-382): 0: 545: 100.00		GOGB1_HUMAN (1119-1866): 1.3e-10: 71.3: 6.59
+	Hs
		297813 CXA1_HUMAN (1-382): 0: 545: 100.00		K0754_HUMAN (1218-1826): 6.86e-10: 69: 10.48
+	Hs
		963365 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95
+	Hs
		164637 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		SPTN2_HUMAN (5708-7163): 4.91e-17: 92.5: 14.91
+	Hs
		1045454 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42
+	Hs
		1230304 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		SYNE2_HUMAN (282-1774): 1.65e-12: 77.9: 8.82
+	Hs
		1059239 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		GOGB1_HUMAN (1119-1866): 1.3e-10: 71.3: 6.59
+	Hs
		1230284 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		SYNE1_HUMAN (147-1832): 6.65e-10: 69: 8.83