HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: GRDN (Q3V6T2)
Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)
Gene: CCDC88A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 35391932
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 1871
+	Hs
		1113806 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		GRDN_HUMAN (1-1871): 2.19e-149: 509: 100.00
+	Hs
		567045 CXA1_HUMAN (1-382): 0: 545: 100.00		GOGA4_HUMAN (1253-1786): 2.42e-13: 78.1: 7.84
+	Hs
		528358 CXA1_HUMAN (1-382): 0: 545: 100.00		MYH6_HUMAN (1-400): 1.3e-10: 69.2: 12.47
+	Rn
		361108 CXA1_RAT (1-382): 0: 546: 97.64		MYH7_RAT (1-391): 3.04e-10: 67.7: 12.25
+	Hs
		522587 CXA1_HUMAN (1-382): 0: 545: 100.00		MYH7_HUMAN (1-391): 2.32e-10: 68.1: 12.25
+	Hs
		254446 CXA1_HUMAN (1-382): 0: 545: 100.00		ROCK2_HUMAN (244-1010): 3.06e-09: 64.3: 20.76
+	Hs
		1034601 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		GOGA4_HUMAN (1253-1786): 2.42e-13: 78.1: 7.84