HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: S39AC (Q504Y0)
Zinc transporter ZIP12 (LIV-1 subfamily of ZIP zinc transporter 8) (LZT-Hs8) (Solute carrier family 39 member 12) (Zrt- and Irt-like protein 12) (ZIP-12)
Gene: SLC39A12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 691
+	Hs
		734412 CXG1_HUMAN (4-373): 1.81e-130: 381: 32.49		S39AC_HUMAN (1-691): 0: 906: 100.00
+	Hs
		567324 CXA1_HUMAN (1-382): 0: 545: 100.00		S39AA_HUMAN (257-689): 6.58e-124: 389: 25.41
+	Hs
		567062 CXA1_HUMAN (1-382): 0: 545: 100.00		S39AE_HUMAN (229-691): 1.54e-117: 362: 28.23
+	Hs
		567044 CXA1_HUMAN (1-382): 0: 545: 100.00		S39A6_HUMAN (278-689): 1.57e-109: 350: 25.86
+	Hs
		567118 CXA1_HUMAN (1-382): 0: 545: 100.00		S39A4_HUMAN (227-689): 2.85e-108: 343: 34.11
+	Hs
		1230423 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		S39AA_HUMAN (257-689): 6.58e-124: 389: 25.41
+	Hs
		816618 CXA8_HUMAN (1-382): 1.55e-135: 395: 37.81		S39A7_HUMAN (352-686): 5.57e-78: 258: 26.91
+	Hs
		1065484 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		S39AE_HUMAN (229-691): 1.54e-117: 362: 28.23
+	Hs
		1034234 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		S39A6_HUMAN (278-689): 1.57e-109: 350: 25.86
+	Hs
		816650 CXA8_HUMAN (1-382): 1.55e-135: 395: 37.81		S39A2_HUMAN (372-686): 5.02e-51: 181: 14.91
+	Hs
		816655 CXA8_HUMAN (1-382): 1.55e-135: 395: 37.81		S39A9_HUMAN (371-684): 3.07e-47: 171: 18.49