Interactor 1: SPI1 (P17433)
Transcription factor PU.1 (31 kDa-transforming protein) (SFFV proviral integration 1 protein)
Gene: SPI1

Interactor 2: SMAD3 (Q8BUN5)
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (mMad3) (SMAD family member 3) (SMAD 3) (Smad3)
Gene: SMAD3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 22036565
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
and 15 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 272
Mm

1 425
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024