Protein: CD53
Leukocyte surface antigen CD53 (Cell surface glycoprotein CD53) (Tetraspanin-25) (Tspan-25) (CD antigen CD53)

Gene: CD53
Organism: Homo sapiens
Interactions: 100
UniProt ID: P19397

Gene Ontology (top 5):
GO:0001772 - immunological synapse
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0007165 - signal transduction
GO:0009986 - cell surface

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

276303

UPK1B
Uroplakin-1b

2

17

High-throughput

0.783

High

502889

CD37
Leukocyte antigen CD37

2

19

High-throughput

0.783

High

583854

CD53
Leukocyte surface antigen CD53

2

19

High-throughput

0.783

High

583857

CD9
CD9 antigen

1

18

Small-scale

0.618

High

583861

CD82
CD82 antigen

1

19

Small-scale

0.618

High

583868

CD81
CD81 antigen

1

19

Small-scale

0.618

High

306755

VAMP5
Vesicle-associated membrane protein 5

2

4

High-throughput

0.606

High

313584

CNIH1
Protein cornichon homolog 1

2

1

High-throughput

0.606

High

315105

CLD7
Claudin-7

2

6

High-throughput

0.606

High

396316

APOD
Apolipoprotein D

2

1

High-throughput

0.606

High

426811

ASGR2
Asialoglycoprotein receptor 2

2

9

High-throughput

0.606

High

554264

MUC1
Mucin-1

2

1

High-throughput

0.606

High

583858

IBP5
Insulin-like growth factor-binding protein 5

2

1

High-throughput

0.606

High

583860

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

2

13

High-throughput

0.606

High

583863

STX2
Syntaxin-2

2

11

High-throughput

0.606

High

583864

CXA8
Gap junction alpha-8 protein

2

5

High-throughput

0.606

High

583866

EFNA5
Ephrin-A5

2

3

High-throughput

0.606

High

583867

EMP1
Epithelial membrane protein 1

2

4

High-throughput

0.606

High

583871

S35A1
CMP-sialic acid transporter

2

1

High-throughput

0.606

High

583872

PMP22
Peripheral myelin protein 22

2

4

High-throughput

0.606

High

583873

IFM3
Interferon-induced transmembrane protein 3

2

5

High-throughput

0.606

High

583874

PLP2
Proteolipid protein 2

2

1

High-throughput

0.606

High

583882

SGMR2
Sigma intracellular receptor 2

2

1

High-throughput

0.606

High

583884

F209A
Protein FAM209A

2

4

High-throughput

0.606

High

583888

VSTM1
V-set and transmembrane domain-containing protein 1

2

3

High-throughput

0.606

High

583897

CLD19
Claudin-19

2

6

High-throughput

0.606

High

583898

KI3L3
Killer cell immunoglobulin-like receptor 3DL3

2

11

High-throughput

0.606

High

583902

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

4

High-throughput

0.606

High

583903

S7A14
Solute carrier family 7 member 14

2

6

High-throughput

0.606

High

583904

GP152
Probable G-protein coupled receptor 152

2

20

High-throughput

0.606

High

583906

BT2A2
Butyrophilin subfamily 2 member A2

2

3

High-throughput

0.606

High

583919

CLC7A
C-type lectin domain family 7 member A

2

14

High-throughput

0.606

High

583928

AIG1
Androgen-induced gene 1 protein

2

2

High-throughput

0.606

High

583929

LPAR3
Lysophosphatidic acid receptor 3

2

19

High-throughput

0.606

High

207424

LAT
Linker for activation of T-cells family member 1

2

0

High-throughput

0.580

High

583876

SMAGP
Small cell adhesion glycoprotein

2

0

High-throughput

0.580

High

583879

NKG7
Protein NKG7

2

0

High-throughput

0.580

High

583885

TSPO2
Translocator protein 2

2

0

High-throughput

0.580

High

583912

MS4A3
Membrane-spanning 4-domains subfamily A member 3

2

0

High-throughput

0.580

High

583932

UBIA1
UbiA prenyltransferase domain-containing protein 1

2

0

High-throughput

0.580

High

58277

TM218
Transmembrane protein 218

2

1

High-throughput

0.553

High

583862

CO4A5

2

1

High-throughput

0.553

High

583880

AR13B
ADP-ribosylation factor-like protein 13B

2

2

High-throughput

0.553

High

583881

CTXN3
Cortexin-3

2

1

High-throughput

0.553

High

583886

CNIH2
Protein cornichon homolog 2

2

1

High-throughput

0.553

High

583893

CD302
CD302 antigen

2

8

High-throughput

0.553

High

583895

TR1L1
Translocating chain-associated membrane protein 1-like 1

2

3

High-throughput

0.553

High

583905

GPX8
Probable glutathione peroxidase 8

2

2

High-throughput

0.553

High

583908

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

6

High-throughput

0.553

High

583913

SIAT2
Beta-galactoside alpha-2,6-sialyltransferase 2

2

1

High-throughput

0.553

High

583917

CYBC1
Cytochrome b-245 chaperone 1

2

1

High-throughput

0.553

High

583920

SMIM3
Small integral membrane protein 3

2

1

High-throughput

0.553

High

583923

GP108
Protein GPR108

2

4

High-throughput

0.553

High

583924

SAR1A
Small COPII coat GTPase SAR1A

2

2

High-throughput

0.553

High

583926

TM140
Transmembrane protein 140

2

1

High-throughput

0.553

High

205027

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.536

High

583869

RAP1A
Ras-related protein Rap-1A

1

2

High-throughput

0.536

High

583878

VAMP3
Vesicle-associated membrane protein 3

1

4

High-throughput

0.536

High

484506

ECE2
Endothelin-converting enzyme 2

1

8

High-throughput

0.515

High

583875

KDSR
3-ketodihydrosphingosine reductase

1

9

High-throughput

0.489

High

583891

RETR3
Reticulophagy regulator 3

1

6

High-throughput

0.489

High

583901

MFSD8
Major facilitator superfamily domain-containing protein 8

1

2

High-throughput

0.489

High

583907

TM186
Transmembrane protein 186

1

3

High-throughput

0.489

High

583909

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

2

High-throughput

0.489

High

583911

ALG14
UDP-N-acetylglucosamine transferase subunit ALG14

1

1

High-throughput

0.489

High

583914

F210B
Protein FAM210B, mitochondrial

1

6

High-throughput

0.489

High

583915

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

3

High-throughput

0.489

High

583927

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

3

High-throughput

0.489

High

583931

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

1

1

High-throughput

0.489

High

583894

TARG1
Trafficking regulator of GLUT4 1

1

2

High-throughput

0.481

High

583921

CXL16
C-X-C motif chemokine 16

1

1

High-throughput

0.481

High

416916

CD2
T-cell surface antigen CD2

1

10

Small-scale

0.479

High

566277

KPCA
Protein kinase C alpha type

1

2

Small-scale

0.479

High

583855

GGT1
Glutathione hydrolase 1 proenzyme

1

2

Small-scale

0.479

High

61008

A5PKU2
TUSC5 protein

1

2

High-throughput

0.470

High

63220

RP1BL
Ras-related protein Rap-1b-like protein

1

3

High-throughput

0.445

High

583887

SCIMP
SLP adapter and CSK-interacting membrane protein

1

1

Small-scale

0.445

High

583890

CCD81
Coiled-coil domain-containing protein 81

1

1

Small-scale

0.407

High

56455

SRTM1
Serine-rich and transmembrane domain-containing protein 1

2

0

High-throughput

0.316

High

123361

GET1
Guided entry of tail-anchored proteins factor 1

2

0

High-throughput

0.316

High

583856

MAL
Myelin and lymphocyte protein

2

0

High-throughput

0.316

High

583859

PPLA
Cardiac phospholamban

2

0

High-throughput

0.316

High

583865

CLCN7
H(+)/Cl(-) exchange transporter 7

2

0

High-throughput

0.316

High

583877

BIK
Bcl-2-interacting killer

2

0

High-throughput

0.316

High

583883

TM128
Transmembrane protein 128

2

0

High-throughput

0.316

High

583889

SNORC
Protein SNORC

2

0

High-throughput

0.316

High

583892

C1QL4
Complement C1q-like protein 4

2

0

High-throughput

0.316

High

583896

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.316

High

583899

LSME1
Leucine-rich single-pass membrane protein 1

2

0

High-throughput

0.316

High

583900

T229B
Transmembrane protein 229B

2

0

High-throughput

0.316

High

583910

GIMA5
GTPase IMAP family member 5

2

0

High-throughput

0.316

High

583916

TM237
Transmembrane protein 237

2

0

High-throughput

0.316

High

583918

B2L13
Bcl-2-like protein 13

2

0

High-throughput

0.316

High

583922

TMM60
Transmembrane protein 60

2

0

High-throughput

0.316

High

583925

RPRM
Protein reprimo

2

0

High-throughput

0.316

High

583930

ERG28
Ergosterol biosynthetic protein 28 homolog

2

0

High-throughput

0.316

High

68136

F1712
Protein FAM171A2

1

0

High-throughput

0.279

Low

483844

DWORF
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

1

0

High-throughput

0.268

Low

583870

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.261

Low


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Last updated: 15 Jul 2024