HitPredict

Interactor 1: JUND (P17535)
Transcription factor JunD (Transcription factor AP-1 subunit JunD)
Gene: JUND

Interactor 2: MK08 (P45983)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: MAPK8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	12052834, 16264271
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0019899 - enzyme binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 347 Hs			1 427
+	Hs
		568080 JUND_HUMAN (1-347): 5.24e-75: 236: 100.00		MK10_HUMAN (1-427): 6.5e-163: 468: 90.16
+	Hs
		568074 JUND_HUMAN (1-347): 5.24e-75: 236: 100.00		MK09_HUMAN (1-427): 5.18e-163: 467: 80.80
+	Hs
		401592 JUN_HUMAN (1-347): 1.06e-67: 217: 49.17		MK08_HUMAN (1-427): 6.2e-164: 469: 100.00
+	Hs
		401690 JUN_HUMAN (1-347): 1.06e-67: 217: 49.17		MK10_HUMAN (1-427): 6.5e-163: 468: 90.16
+	Rn
		567365 JUN_RAT (1-347): 1.23e-67: 217: 49.18		MK10_RAT (1-427): 7.66e-163: 468: 90.16
+	Hs
		401593 JUN_HUMAN (1-347): 1.06e-67: 217: 49.17		MK09_HUMAN (1-427): 5.18e-163: 467: 80.80
+	Hs
		566734 JUNB_HUMAN (1-347): 1.77e-64: 209: 38.65		MK08_HUMAN (1-427): 6.2e-164: 469: 100.00
+	Hs
		566735 JUNB_HUMAN (1-347): 1.77e-64: 209: 38.65		MK09_HUMAN (1-427): 5.18e-163: 467: 80.80
+	Rn
		567364 JUN_RAT (1-347): 1.23e-67: 217: 49.18		MK09_RAT (1-427): 9.62e-160: 458: 80.09
+	Rn
		567363 JUN_RAT (1-347): 1.23e-67: 217: 49.18		MK08_RAT (1-411): 9.11e-159: 455: 98.78
+	Mm
		404155 JUN_MOUSE (1-347): 1.96e-67: 216: 49.59		MK08_MOUSE (1-381): 7.75e-152: 437: 99.48
+	Hs
		547742 ATF2_HUMAN (22-347): 5.27e-47: 168: 19.82		MK08_HUMAN (1-427): 6.2e-164: 469: 100.00
+	Hs
		547743 ATF2_HUMAN (22-347): 5.27e-47: 168: 19.82		MK09_HUMAN (1-427): 5.18e-163: 467: 80.80
+	Hs
		402080 JUN_HUMAN (1-347): 1.06e-67: 217: 49.17		MK14_HUMAN (4-365): 2.33e-130: 381: 46.03
+	Hs
		173828 ATF2_HUMAN (22-347): 5.27e-47: 168: 19.82		MK13_HUMAN (6-373): 1.37e-129: 380: 45.14
+	Hs
		568066 JUND_HUMAN (1-347): 5.24e-75: 236: 100.00		MK01_HUMAN (20-359): 2.94e-84: 263: 42.98
+	Hs
		401473 JUN_HUMAN (1-347): 1.06e-67: 217: 49.17		MK01_HUMAN (20-359): 2.94e-84: 263: 42.98
+	Hs
		401456 JUN_HUMAN (1-347): 1.06e-67: 217: 49.17		MK03_HUMAN (20-359): 5.22e-83: 261: 41.26
+	Hs
		547713 ATF2_HUMAN (22-347): 5.27e-47: 168: 19.82		MK01_HUMAN (20-359): 2.94e-84: 263: 42.98
+	Hs
		547709 ATF2_HUMAN (22-347): 5.27e-47: 168: 19.82		MK03_HUMAN (20-359): 5.22e-83: 261: 41.26