HitPredict

Interactor 1: ATF7 (P17544)
Cyclic AMP-dependent transcription factor ATF-7 (cAMP-dependent transcription factor ATF-7) (Activating transcription factor 7) (Transcription factor ATF-A)
Gene: ATF7

Interactor 2: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34316702
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 483 Hs			1 326
+	Hs
		579126 ATF1_HUMAN (110-383): 5.11e-32: 125: 15.33		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		556779 CREB1_HUMAN (89-383): 4.8e-27: 112: 15.25		RO52_HUMAN (5-198): 5.75e-52: 180: 18.78
+	Hs
		556914 CREB1_HUMAN (89-383): 4.8e-27: 112: 15.25		TRI22_HUMAN (1-198): 2.92e-50: 175: 14.56
+	Hs
		401886 JUN_HUMAN (94-409): 4.25e-45: 162: 15.89		RING1_HUMAN (7-115): 2.38e-30: 120: 25.46
+	Hs
		556963 CREB1_HUMAN (89-383): 4.8e-27: 112: 15.25		TRIM5_HUMAN (9-190): 3.01e-48: 170: 14.89
+	Hs
		216715 CREB3_HUMAN (209-437): 5.57e-24: 105: 17.92		TRI26_HUMAN (5-210): 1e-49: 175: 16.59