Protein: TET5C
Terminal nucleotidyltransferase 5C (EC 2.7.7.19) (Non-canonical poly(A) polymerase FAM46C)

Gene: TET5C, TENT5C
Organism: Homo sapiens
Interactions: 139
UniProt ID: Q5VWP2

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

136098

PLK4
Serine/threonine-protein kinase PLK4

1

3

High-throughput

0.698

High

1219007

FND3A
Fibronectin type-III domain-containing protein 3A

2

3

Small-scale

0.624

High

1218997

BCCIP
BRCA2 and CDKN1A-interacting protein

1

3

High-throughput

0.618

High

1150734

SF01
Splicing factor 1

2

1

High-throughput

0.576

High

1218987

RHXF2
Rhox homeobox family member 2

1

4

High-throughput

0.573

High

241960

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.541

High

1139057

DAZP2
DAZ-associated protein 2

1

1

High-throughput

0.541

High

1151534

TRIP6
Thyroid receptor-interacting protein 6

1

0

High-throughput

0.518

High

1131958

MVP
Major vault protein

1

2

High-throughput

0.481

High

215312

TXNL1
Thioredoxin-like protein 1

1

1

High-throughput

0.479

High

295189

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

1

High-throughput

0.479

High

300163

GLRX3
Glutaredoxin-3

1

2

High-throughput

0.479

High

402610

ALDOA
Fructose-bisphosphate aldolase A

1

1

High-throughput

0.479

High

451001

LDHB
L-lactate dehydrogenase B chain

1

2

High-throughput

0.479

High

476157

ANXA5
Annexin A5

1

1

High-throughput

0.479

High

568247

PLST
Plastin-3

1

1

High-throughput

0.479

High

575143

IDE
Insulin-degrading enzyme

1

2

High-throughput

0.479

High

582097

PGAM2
Phosphoglycerate mutase 2

1

1

High-throughput

0.479

High

616191

PGAM1
Phosphoglycerate mutase 1

1

1

High-throughput

0.479

High

627979

ANXA7
Annexin A7

1

1

High-throughput

0.479

High

650804

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

2

High-throughput

0.479

High

665445

EF1B
Elongation factor 1-beta

1

1

High-throughput

0.479

High

680907

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.479

High

681180

PSA2
Proteasome subunit alpha type-2

1

2

High-throughput

0.479

High

681408

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.479

High

700906

PSB4
Proteasome subunit beta type-4

1

4

High-throughput

0.479

High

714889

EF1D
Elongation factor 1-delta

1

1

High-throughput

0.479

High

716302

PRDX6
Peroxiredoxin-6

1

1

High-throughput

0.479

High

729305

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

3

High-throughput

0.479

High

732335

PRDX2
Peroxiredoxin-2

1

1

High-throughput

0.479

High

822151

PSB10
Proteasome subunit beta type-10

1

1

High-throughput

0.479

High

828659

MDHC
Malate dehydrogenase, cytoplasmic

1

2

High-throughput

0.479

High

828808

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

851348

PRS6B
26S proteasome regulatory subunit 6B

1

1

High-throughput

0.479

High

932475

KAD2
Adenylate kinase 2, mitochondrial

1

1

High-throughput

0.479

High

938738

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

3

High-throughput

0.479

High

954831

PSA6
Proteasome subunit alpha type-6

1

2

High-throughput

0.479

High

968731

PRS4
26S proteasome regulatory subunit 4

1

1

High-throughput

0.479

High

990336

1433Z
14-3-3 protein zeta/delta

1

1

High-throughput

0.479

High

1024628

VIGLN
Vigilin

1

3

High-throughput

0.479

High

1054601

PSME1
Proteasome activator complex subunit 1

1

1

High-throughput

0.479

High

1059866

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

1

High-throughput

0.479

High

1100827

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.479

High

1120196

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

2

High-throughput

0.479

High

1156375

SEPT7
Septin-7

1

1

High-throughput

0.479

High

1218978

NDRG1
Protein NDRG1

1

2

High-throughput

0.479

High

1218991

CSN7B
COP9 signalosome complex subunit 7b

1

1

High-throughput

0.479

High

1218998

SEPT9
Septin-9

1

1

High-throughput

0.479

High

1218999

KAD3
GTP:AMP phosphotransferase AK3, mitochondrial

1

1

High-throughput

0.479

High

1219001

PSME2
Proteasome activator complex subunit 2

1

1

High-throughput

0.479

High

1219002

UBQL1
Ubiquilin-1

1

3

High-throughput

0.479

High

1219003

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

High-throughput

0.479

High

187731

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

0

High-throughput

0.458

High

224726

ACTN4
Alpha-actinin-4

1

0

High-throughput

0.458

High

255817

USO1
General vesicular transport factor p115

1

0

High-throughput

0.458

High

296051

IDHC
Isocitrate dehydrogenase [NADP] cytoplasmic

1

0

High-throughput

0.458

High

343601

OXSR1
Serine/threonine-protein kinase OSR1

1

0

High-throughput

0.458

High

360014

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.458

High

361891

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.458

High

445917

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

447104

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

464272

FUMH
Fumarate hydratase, mitochondrial

1

0

High-throughput

0.458

High

489044

LKHA4
Leukotriene A-4 hydrolase

1

0

High-throughput

0.458

High

539190

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.458

High

552610

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.458

High

572019

TRI27
Zinc finger protein RFP

1

0

Small-scale

0.458

High

621662

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

705824

AMPL
Cytosol aminopeptidase

1

0

High-throughput

0.458

High

766626

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

786335

PGM1
Phosphoglucomutase-1

1

0

High-throughput

0.458

High

788062

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.458

High

884758

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

911838

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

1

0

High-throughput

0.458

High

929797

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

938060

TPD52
Tumor protein D52

1

0

High-throughput

0.458

High

949163

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

971629

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.458

High

1007844

GSTO1
Glutathione S-transferase omega-1

1

0

High-throughput

0.458

High

1058461

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

1095209

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

0

High-throughput

0.458

High

1107815

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

1110627

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

1117096

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.458

High

1134611

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.458

High

1144766

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

1

0

High-throughput

0.458

High

1148850

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

0

High-throughput

0.458

High

1152103

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.458

High

1191421

GRDN
Girdin

1

0

High-throughput

0.458

High

1218973

CPIN1
Anamorsin

1

0

High-throughput

0.458

High

1218974

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.458

High

1218976

CCAR2
Cell cycle and apoptosis regulator protein 2

1

0

High-throughput

0.458

High

1218977

NNRE
NAD(P)H-hydrate epimerase

1

0

High-throughput

0.458

High

1218979

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.458

High

1218980

FUBP2
Far upstream element-binding protein 2

1

0

High-throughput

0.458

High

1218981

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1218983

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.458

High

1218984

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.458

High

1218986

CPNE1
Copine-1

1

0

High-throughput

0.458

High

1218988

AN32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E

1

0

High-throughput

0.458

High

1218990

EHD4
EH domain-containing protein 4

1

0

High-throughput

0.458

High

1218993

NIT2
Omega-amidase NIT2

1

0

High-throughput

0.458

High

1218995

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.458

High

1219004

NSF1C
NSFL1 cofactor p47

1

0

High-throughput

0.458

High

1219005

SMC3
Structural maintenance of chromosomes protein 3

1

0

High-throughput

0.458

High

1219006

NUDC
Nuclear migration protein nudC

1

0

High-throughput

0.458

High

1219009

RTCB
RNA-splicing ligase RtcB homolog

1

0

High-throughput

0.458

High

1219010

X5D7R7
Major vault protein

1

2

High-throughput

0.457

High

1219011

X5DP17
Major vault protein isoform H

1

2

High-throughput

0.457

High

479213

THIK
3-ketoacyl-CoA thiolase, peroxisomal

1

1

High-throughput

0.437

High

489098

ALDOC
Fructose-bisphosphate aldolase C

1

1

High-throughput

0.437

High

666308

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

1

High-throughput

0.437

High

1148244

RSU1
Ras suppressor protein 1

1

1

High-throughput

0.437

High

1218975

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

1

High-throughput

0.437

High

989000

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.282

High

299993

CBPD
Carboxypeptidase D

1

0

High-throughput

0.249

Low

365398

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.249

Low

412961

CPNS1
Calpain small subunit 1

1

0

High-throughput

0.249

Low

458914

HEXB
Beta-hexosaminidase subunit beta

1

0

High-throughput

0.249

Low

568432

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

572719

AK1A1
Aldo-keto reductase family 1 member A1

1

0

High-throughput

0.249

Low

608890

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

0

High-throughput

0.249

Low

637106

VATC1
V-type proton ATPase subunit C 1

1

0

High-throughput

0.249

Low

728953

PUR9
Bifunctional purine biosynthesis protein ATIC

1

0

High-throughput

0.249

Low

789906

FDFT
Squalene synthase

1

0

High-throughput

0.249

Low

849463

NAMPT
Nicotinamide phosphoribosyltransferase

1

0

High-throughput

0.249

Low

1054222

PUR1
Amidophosphoribosyltransferase

1

0

High-throughput

0.249

Low

1142298

PDIA6
Protein disulfide-isomerase A6

1

0

High-throughput

0.249

Low

1152798

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.249

Low

1158663

DPYL2
Dihydropyrimidinase-related protein 2

1

0

High-throughput

0.249

Low

1162368

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1180671

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

0

High-throughput

0.249

Low

1218982

SUCB2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

0

High-throughput

0.249

Low

1218985

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.249

Low

1218989

PBDC1
Protein PBDC1

1

0

High-throughput

0.249

Low

1218992

GLOD4
Glyoxalase domain-containing protein 4

1

0

High-throughput

0.249

Low

1218994

SAR1A
Small COPII coat GTPase SAR1A

1

0

High-throughput

0.249

Low

1218996

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.249

Low

1219000

STML2
Stomatin-like protein 2, mitochondrial

1

0

High-throughput

0.249

Low

1219008

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025