HitPredict

Interactor 1: ATF7 (P17544)
Cyclic AMP-dependent transcription factor ATF-7 (cAMP-dependent transcription factor ATF-7) (Activating transcription factor 7) (Transcription factor ATF-A)
Gene: ATF7

Interactor 2: MK08 (P45983)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: MAPK8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11566021
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0019899 - enzyme binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 483 Hs			1 427
+	Hs
		547742 ATF2_HUMAN (1-475): 1.31e-81: 263: 54.97		MK08_HUMAN (1-427): 6.2e-164: 469: 100.00
+	Hs
		547757 ATF2_HUMAN (1-475): 1.31e-81: 263: 54.97		MK10_HUMAN (1-427): 6.5e-163: 468: 90.16
+	Hs
		547743 ATF2_HUMAN (1-475): 1.31e-81: 263: 54.97		MK09_HUMAN (1-427): 5.18e-163: 467: 80.80
+	Mm
		562984 ATF2_MOUSE (1-480): 9.52e-76: 247: 54.82		MK09_MOUSE (1-427): 1.29e-160: 460: 81.50
+	Mm
		562982 ATF2_MOUSE (1-480): 9.52e-76: 247: 54.82		MK08_MOUSE (1-381): 7.75e-152: 437: 99.48
+	Hs
		547805 ATF2_HUMAN (1-475): 1.31e-81: 263: 54.97		MK11_HUMAN (4-363): 2.3e-137: 399: 47.11
+	Mm
		562985 ATF2_MOUSE (1-480): 9.52e-76: 247: 54.82		MK11_MOUSE (4-365): 2.02e-137: 399: 46.85
+	Hs
		547811 ATF2_HUMAN (1-475): 1.31e-81: 263: 54.97		MK14_HUMAN (4-365): 2.33e-130: 381: 46.03
+	Hs
		173828 ATF2_HUMAN (1-475): 1.31e-81: 263: 54.97		MK13_HUMAN (6-373): 1.37e-129: 380: 45.14
+	Rn
		102456 ATF2_RAT (1-480): 1.35e-76: 250: 50.71		G3V617_RAT (4-365): 6.67e-131: 383: 46.03
+	Hs
		401592 JUN_HUMAN (94-409): 4.25e-45: 162: 15.89		MK08_HUMAN (1-427): 6.2e-164: 469: 100.00
+	Hs
		401690 JUN_HUMAN (94-409): 4.25e-45: 162: 15.89		MK10_HUMAN (1-427): 6.5e-163: 468: 90.16
+	Hs
		401593 JUN_HUMAN (94-409): 4.25e-45: 162: 15.89		MK09_HUMAN (1-427): 5.18e-163: 467: 80.80
+	Mm
		562973 ATF2_MOUSE (1-480): 9.52e-76: 247: 54.82		MK14_MOUSE (4-365): 9.55e-131: 382: 46.03
+	Hs
		547713 ATF2_HUMAN (1-475): 1.31e-81: 263: 54.97		MK01_HUMAN (20-359): 2.94e-84: 263: 42.98
+	Hs
		547709 ATF2_HUMAN (1-475): 1.31e-81: 263: 54.97		MK03_HUMAN (20-359): 5.22e-83: 261: 41.26
+	Mm
		562975 ATF2_MOUSE (1-480): 9.52e-76: 247: 54.82		MK01_MOUSE (20-359): 2.95e-84: 263: 42.98
+	Mm
		562980 ATF2_MOUSE (1-480): 9.52e-76: 247: 54.82		MK03_MOUSE (20-370): 9.11e-84: 263: 40.56
+	Hs
		401473 JUN_HUMAN (94-409): 4.25e-45: 162: 15.89		MK01_HUMAN (20-359): 2.94e-84: 263: 42.98
+	Hs
		401456 JUN_HUMAN (94-409): 4.25e-45: 162: 15.89		MK03_HUMAN (20-359): 5.22e-83: 261: 41.26