Interactor 1: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Interactor 2: IPKA (P61925)
cAMP-dependent protein kinase inhibitor alpha (PKI-alpha) (cAMP-dependent protein kinase inhibitor, muscle/brain isoform)
Gene: PKIA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.866

The method score is based on:

Property Details
Experiments 8027074, 35271311, 32707033
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PKI~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 351
Hs

1 76
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024