HitPredict

Interactor 1: CEBPB (P17676)
CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5)
Gene: CEBPB

Interactor 2: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30884312
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 345 Hs			1 411
+	Hs
		569482 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		IF4A1_HUMAN (7-411): 1.67e-178: 505: 66.75
+	Hs
		831158 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		IF4A1_HUMAN (7-411): 1.67e-178: 505: 66.75
+	Hs
		569145 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		DDX5_HUMAN (25-411): 6.87e-135: 401: 30.63
+	Hs
		569930 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		DDX17_HUMAN (14-411): 1.24e-132: 399: 30.79
+	Hs
		133872 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Hs
		757510 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00
+	Mm
		862865 CEBPA_MOUSE (24-345): 2.92e-47: 165: 29.79		IF4A3_MOUSE (1-411): 5.56e-143: 415: 99.27
+	Hs
		571357 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		DDX5_HUMAN (25-411): 6.87e-135: 401: 30.63
+	Hs
		831541 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		DDX17_HUMAN (14-411): 1.24e-132: 399: 30.79
+	Hs
		133929 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45
+	Mm
		558496 CEBPA_MOUSE (24-345): 2.92e-47: 165: 29.79		DDX3L_MOUSE (17-410): 1.2e-129: 389: 32.45
+	Hs
		569215 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		DDX6_HUMAN (35-407): 1.15e-88: 278: 37.83
+	Hs
		640373 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		DDX6_HUMAN (35-407): 1.15e-88: 278: 37.83