HitPredict

Interactor 1: CEBPB (P17676)
CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5)
Gene: CEBPB

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30884312
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0016363 - nuclear matrix GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 345 Hs			1 1214
+	Hs
		569936 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		831510 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		831547 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		727167 DDIT3_HUMAN (213-332): 7.77e-24: 97.9: 20.33		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		727175 DDIT3_HUMAN (213-332): 7.77e-24: 97.9: 20.33		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		231994 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		570236 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261397 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		232052 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Mm
		862837 CEBPA_MOUSE (24-345): 2.92e-47: 165: 29.79		KDM1A_MOUSE (254-543): 9.03e-44: 174: 15.05
+	Hs
		569452 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		SC24C_HUMAN (1005-1213): 5.27e-13: 75.8: 19.28
+	Hs
		297849 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		SC24D_HUMAN (951-1204): 5.56e-13: 75.7: 25.44
+	Hs
		831855 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261438 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		831502 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		KMT2C_HUMAN (650-1128): 8.15e-09: 62.4: 8.57
+	Mm
		70898 CEBPB_MOUSE (1-345): 1.32e-49: 169: 64.35		EP300_MOUSE (885-1214): 8.74e-09: 62.4: 13.78
+	Mm
		70906 CEBPA_MOUSE (24-345): 2.92e-47: 165: 29.79		EP300_MOUSE (885-1214): 8.74e-09: 62.4: 13.78
+	Mm
		70890 ATF2_MOUSE (49-342): 2.38e-36: 138: 17.31		EP300_MOUSE (885-1214): 8.74e-09: 62.4: 13.78